Antimicrobial peptides (AMPs) are important components of innate immunity. They are often
expressed in response to colonic inflammation and infection. Over the last several years, the …

Enterohemorrhagic Escherichia coli (EHEC) are the human pathogenic subset of Shiga
toxin (Stx)-producing E. coli (STEC). EHEC are responsible for severe colon infections …

Enteric pathogens must not only survive passage through the gastrointestinal tract but must
also coordinate expression of virulence determinants in response to localized …

Zoonoses have recently become the center of attention of the general population and
scientific community. Notably, more than 30 new human pathogens have been identified in …

Infection with Shiga toxin-producing Escherichia coli (STEC) results in hemorrhagic colitis
and can lead to life-threatening sequelae including hemolytic uremic syndrome (HUS) …

In about 6% of patients infected with 0157: H7 or other enterohaemorrhagic Escherichia coli
(EHEC) serotypes, bloody diarrhoea is followed by abrupt onset of microangio pathic …

Non-O157 Shiga toxin–producing Escherichia coli (non-O157 STEC) strains have emerged
as important foodborne pathogens worldwide. Non-O157 STEC serogroups O26, O45 …

Background Certain peptides that bind Shiga toxin 2 (Stx2) have been reported to treat
Shiga toxin-producing Escherichia coli (STEC) infections. However, their mechanisms of …

The peptide wrwycr inhibits Holliday junction resolution and is a potent antimicrobial. To
study the physiological effects of wrwycr treatment on Escherichia coli cells, we partially …

Dps, a DNA-binding protein from starved cells in Escherichia coli, is part of the bacterial
defense system that protects DNA against various cellular stresses. Our lab previously …