The reproductive microbiome: an emerging driver of sexual selection, sexual conflict, mating systems, and reproductive isolation
All multicellular organisms host microbial communities in and on their bodies, and these
microbiomes can have major influences on host biology. Most research has focussed on the …
microbiomes can have major influences on host biology. Most research has focussed on the …
Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence
The prevalence and intensity of parasites in wild hosts varies across space and is a key
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …
Divergent selection on locally adapted major histocompatibility complex immune genes experimentally proven in the field
Although crucial for the understanding of adaptive evolution, genetically resolved examples
of local adaptation are rare. To maximize survival and reproduction in their local …
of local adaptation are rare. To maximize survival and reproduction in their local …
Immunogenetic novelty confers a selective advantage in host–pathogen coevolution
KP Phillips, J Cable, RS Mohammed… - Proceedings of the …, 2018 - National Acad Sciences
The major histocompatibility complex (MHC) is crucial to the adaptive immune response of
vertebrates and is among the most polymorphic gene families known. Its high diversity is …
vertebrates and is among the most polymorphic gene families known. Its high diversity is …
The role of parasitism in adaptive radiations—when might parasites promote and when might they constrain ecological speciation?
A Karvonen, O Seehausen - International Journal of Ecology, 2012 - Wiley Online Library
Research on speciation and adaptive radiation has flourished during the past decades, yet
factors underlying initiation of reproductive isolation often remain unknown. Parasites …
factors underlying initiation of reproductive isolation often remain unknown. Parasites …
Parasite diversity, patterns of MHC II variation and olfactory based mate choice in diverging three-spined stickleback ecotypes
Ecological speciation has been the subject of intense research in evolutionary biology but
the genetic basis of the actual mechanism driving reproductive isolation has rarely been …
the genetic basis of the actual mechanism driving reproductive isolation has rarely been …
Major histocompatibility complex polymorphism: dynamics and consequences of parasite‐mediated local adaptation in fishes
C Eizaguirre, TL Lenz - Journal of fish biology, 2010 - Wiley Online Library
Parasitism is a common form of life and represents a strong selective pressure for host
organisms. In response to this evolutionary pressure, vertebrates have developed …
organisms. In response to this evolutionary pressure, vertebrates have developed …
Major histocompatibility complex heterozygote advantage and widespread bacterial infections in populations of Chinook salmon (Oncorhynchus tshawytscha)
Despite growing evidence for parasite‐mediated selection on the vertebrate major
histocompatibility complex (MHC), little is known about variation in the bacterial parasite …
histocompatibility complex (MHC), little is known about variation in the bacterial parasite …
Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen
J Lighten, AST Papadopulos, RS Mohammed… - Nature …, 2017 - nature.com
Red Queen host–parasite co-evolution can drive adaptations of immune genes by positive
selection that erodes genetic variation (Red Queen arms race) or results in a balanced …
selection that erodes genetic variation (Red Queen arms race) or results in a balanced …
[HTML][HTML] The effects of inbreeding on disease susceptibility: Gyrodactylus turnbulli infection of guppies, Poecilia reticulata
W Smallbone, C Van Oosterhout, J Cable - Experimental Parasitology, 2016 - Elsevier
Inbreeding can threaten population persistence by reducing disease resistance through the
accelerated loss of gene diversity (ie heterozygosity). Such inbreeding depression can affect …
accelerated loss of gene diversity (ie heterozygosity). Such inbreeding depression can affect …