The reproductive microbiome: an emerging driver of sexual selection, sexual conflict, mating systems, and reproductive isolation

M Rowe, L Veerus, P Trosvik, A Buckling… - Trends in ecology & …, 2020 - cell.com
All multicellular organisms host microbial communities in and on their bodies, and these
microbiomes can have major influences on host biology. Most research has focussed on the …

Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence

DJ Becker, GF Albery, MK Kessler… - Journal of Animal …, 2020 - Wiley Online Library
The prevalence and intensity of parasites in wild hosts varies across space and is a key
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …

Divergent selection on locally adapted major histocompatibility complex immune genes experimentally proven in the field

C Eizaguirre, TL Lenz, M Kalbe, M Milinski - Ecology letters, 2012 - Wiley Online Library
Although crucial for the understanding of adaptive evolution, genetically resolved examples
of local adaptation are rare. To maximize survival and reproduction in their local …

Immunogenetic novelty confers a selective advantage in host–pathogen coevolution

KP Phillips, J Cable, RS Mohammed… - Proceedings of the …, 2018 - National Acad Sciences
The major histocompatibility complex (MHC) is crucial to the adaptive immune response of
vertebrates and is among the most polymorphic gene families known. Its high diversity is …

The role of parasitism in adaptive radiations—when might parasites promote and when might they constrain ecological speciation?

A Karvonen, O Seehausen - International Journal of Ecology, 2012 - Wiley Online Library
Research on speciation and adaptive radiation has flourished during the past decades, yet
factors underlying initiation of reproductive isolation often remain unknown. Parasites …

Parasite diversity, patterns of MHC II variation and olfactory based mate choice in diverging three-spined stickleback ecotypes

C Eizaguirre, TL Lenz, RD Sommerfeld, C Harrod… - Evolutionary …, 2011 - Springer
Ecological speciation has been the subject of intense research in evolutionary biology but
the genetic basis of the actual mechanism driving reproductive isolation has rarely been …

Major histocompatibility complex polymorphism: dynamics and consequences of parasite‐mediated local adaptation in fishes

C Eizaguirre, TL Lenz - Journal of fish biology, 2010 - Wiley Online Library
Parasitism is a common form of life and represents a strong selective pressure for host
organisms. In response to this evolutionary pressure, vertebrates have developed …

Major histocompatibility complex heterozygote advantage and widespread bacterial infections in populations of Chinook salmon (Oncorhynchus tshawytscha)

ML Evans, BD Neff - Molecular ecology, 2009 - Wiley Online Library
Despite growing evidence for parasite‐mediated selection on the vertebrate major
histocompatibility complex (MHC), little is known about variation in the bacterial parasite …

Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen

J Lighten, AST Papadopulos, RS Mohammed… - Nature …, 2017 - nature.com
Red Queen host–parasite co-evolution can drive adaptations of immune genes by positive
selection that erodes genetic variation (Red Queen arms race) or results in a balanced …

[HTML][HTML] The effects of inbreeding on disease susceptibility: Gyrodactylus turnbulli infection of guppies, Poecilia reticulata

W Smallbone, C Van Oosterhout, J Cable - Experimental Parasitology, 2016 - Elsevier
Inbreeding can threaten population persistence by reducing disease resistance through the
accelerated loss of gene diversity (ie heterozygosity). Such inbreeding depression can affect …