[HTML][HTML] Glucagon-like peptide 1 (GLP-1)

TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

Cardiovascular actions and clinical outcomes with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

MA Nauck, JJ Meier, MA Cavender, M Abd El Aziz… - Circulation, 2017 - Am Heart Assoc
Potentiation of glucagon-like peptide-1 (GLP-1) action through selective GLP-1 receptor
(GLP-1R) agonism or by prevention of enzymatic degradation by inhibition of dipeptidyl …

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …

WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

The emerging role of glucagon-like peptide-1 receptor agonists for the management of NAFLD

C Patel Chavez, K Cusi… - The Journal of Clinical …, 2022 - academic.oup.com
Context The burden of cirrhosis from nonalcoholic fatty liver disease (NAFLD) is reaching
epidemic proportions in the United States. This calls for greater awareness among …

[HTML][HTML] Update on the impact, diagnosis and management of cardiovascular autonomic neuropathy in diabetes: what is defined, what is new, and what is unmet

V Spallone - Diabetes & metabolism journal, 2019 - synapse.koreamed.org
The burden of diabetic cardiovascular autonomic neuropathy (CAN) is expected to increase
due to the diabetes epidemic and its early and widespread appearance. CAN has a definite …

Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes …

B Ahrén, L Masmiquel, H Kumar, M Sargin… - The lancet Diabetes & …, 2017 - thelancet.com
Background Semaglutide is a novel glucagon-like peptide-1 (GLP-1) analogue, suitable for
once-weekly subcutaneous administration, in development for treatment of type 2 diabetes …

Efficacy and safety of glucagon‐like peptide‐1 receptor agonists in type 2 diabetes: a systematic review and mixed‐treatment comparison analysis

ZZ Htike, F Zaccardi, D Papamargaritis… - Diabetes, Obesity …, 2017 - Wiley Online Library
Aims To compare efficacy and safety of glucagon‐like peptide‐1 receptor agonists (GLP‐
1RAs) in people with type 2 diabetes. Materials and methods We electronically searched, up …

GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes

MHA Muskiet, L Tonneijck, MM Smits… - Nature Reviews …, 2017 - nature.com
The gastrointestinal tract—the largest endocrine network in human physiology—
orchestrates signals from the external environment to maintain neural and hormonal control …

American Association of Clinical Endocrinology Consensus Statement: comprehensive type 2 diabetes management algorithm–2023 update

SL Samson, P Vellanki, L Blonde, EA Christofides… - Endocrine Practice, 2023 - Elsevier
Objective This consensus statement provides (1) visual guidance in concise graphic
algorithms to assist with clinical decision-making of health care professionals in the …

Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus

AA Tahrani, AH Barnett, CJ Bailey - Nature Reviews Endocrinology, 2016 - nature.com
Type 2 diabetes mellitus (T2DM) is a global epidemic that poses a major challenge to health-
care systems. Improving metabolic control to approach normal glycaemia (where practical) …