Phytochemicals as anti-inflammatory agents in animal models of prevalent inflammatory diseases

SA Shin, BJ Joo, JS Lee, G Ryu, M Han, WY Kim… - Molecules, 2020 - mdpi.com
Phytochemicals are known to have anti-inflammatory effects in vitro and in vivo, such as in
inflammatory disease model systems. Inflammation is an essential immune response to …

Resveratrol and diabetes: A critical review of clinical studies

E Öztürk, AKK Arslan, MB Yerer, A Bishayee - Biomedicine & …, 2017 - Elsevier
Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia. The disease
results from the defects of insulin secretion and/or action. Resveratrol is a non-flavonoid …

Bioactive metabolites from marine algae as potent pharmacophores against oxidative stress-associated human diseases: A comprehensive review

B Pradhan, R Nayak, S Patra, BP Jit, A Ragusa, M Jena - Molecules, 2020 - mdpi.com
In addition to cancer and diabetes, inflammatory and ROS-related diseases represent one of
the major health problems worldwide. Currently, several synthetic drugs are used to reduce …

[HTML][HTML] Carbotoxicity—noxious effects of carbohydrates

G Kroemer, C López-Otín, F Madeo, R de Cabo - Cell, 2018 - cell.com
Modern nutrition is often characterized by the excessive intake of different types of
carbohydrates ranging from digestible polysaccharides to refined sugars that collectively …

Diabetes pharmacotherapy and effects on the musculoskeletal system

E Kalaitzoglou, JL Fowlkes, I Popescu… - … research and reviews, 2019 - Wiley Online Library
Persons with type 1 or type 2 diabetes have a significantly higher fracture risk than age‐
matched persons without diabetes, attributed to disease‐specific deficits in the …

Antidiabetic activities of alkaloids isolated from medicinal plants

I Muhammad, N Rahman, U Nishan… - Brazilian Journal of …, 2021 - SciELO Brasil
Diabetes mellitus is a metabolic disorder affecting a great part of population around the
world. It is the fifth leading death causing disease in the world and its cases are increasing …

In Vitro Antidiabetic Activity and Mechanism of Action of Brachylaena elliptica (Thunb.) DC

IJ Sagbo, M van de Venter… - Evidence‐Based …, 2018 - Wiley Online Library
In South Africa, the number of people suffering from diabetes is believed to be rising steadily
and the current antidiabetic therapies are frequently reported to have adverse side effects …

[HTML][HTML] The structural basis for the binding of repaglinide to the pancreatic KATP channel

D Ding, M Wang, JX Wu, Y Kang, L Chen - Cell reports, 2019 - cell.com
Repaglinide (RPG) is a short-acting insulin secretagogue widely prescribed for the treatment
of type 2 diabetes. It boosts insulin secretion by inhibiting the pancreatic ATP-sensitive …

The anti-diabetic potential of baicalin: evidence from rodent studies

T Szkudelski, K Szkudelska - International Journal of Molecular Sciences, 2023 - mdpi.com
Baicalin is a biologically active flavonoid compound that benefits the organism in various
pathological conditions. Rodent studies have shown that this compound effectively …

Mechanistic approach of anti-diabetic compounds identified from natural sources

R Dabur, B Sharma, A Mittal - Chemical Biology Letters, 2018 - pubs.iscience.in
Abstract Type-2 diabetes mellitus (T2DM) is a global disease, which leads to various other
life threatening diseases and affects the quality of life. Current therapies of T2DM have …