The microbiome in early life: implications for health outcomes

S Tamburini, N Shen, HC Wu, JC Clemente - Nature medicine, 2016 - nature.com
Recent studies have characterized how host genetics, prenatal environment and delivery
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …

[HTML][HTML] History of Helicobacter pylori, duodenal ulcer, gastric ulcer and gastric cancer

DY Graham - World Journal of Gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection underlies gastric ulcer disease, gastric cancer and
duodenal ulcer disease. The disease expression reflects the pattern and extent of …

Mechanisms of disease: Helicobacter pylori virulence factors

Y Yamaoka - Nature reviews Gastroenterology & hepatology, 2010 - nature.com
Helicobacter pylori plays an essential role in the development of various gastroduodenal
diseases; however, only a small proportion of people infected with H. pylori develop these …

[HTML][HTML] Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer

YH Park, N Kim - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
Atrophic gastritis (AG) and intestinal metaplasia (IM) are the main precursor lesions of
gastric cancer as the incidence of gastric cancer increases in the gastric mucosa involved …

Traces of Human Migrations in Helicobacter pylori Populations

D Falush, T Wirth, B Linz, JK Pritchard, M Stephens… - science, 2003 - science.org
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven
populations and subpopulations with distinct geographical distributions. These modern …

An African origin for the intimate association between humans and Helicobacter pylori

B Linz, F Balloux, Y Moodley, A Manica, H Liu… - Nature, 2007 - nature.com
Infection of the stomach by Helicobacter pylori is ubiquitous among humans. However,
although H. pylori strains from different geographic areas are associated with clear …

Human and Helicobacter pylori coevolution shapes the risk of gastric disease

N Kodaman, A Pazos, BG Schneider… - Proceedings of the …, 2014 - National Acad Sciences
Helicobacter pylori is the principal cause of gastric cancer, the second leading cause of
cancer mortality worldwide. However, H. pylori prevalence generally does not predict cancer …

Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites

H Higashi, R Tsutsumi, A Fujita… - Proceedings of the …, 2002 - National Acad Sciences
Helicobacter pylori is a causative agent of gastritis and peptic ulcer. cagA+ H. pylori strains
are more virulent than cagA− strains and are associated with gastric carcinoma. The cagA …

Functional Adaptation of BabA, the H. pylori ABO Blood Group Antigen Binding Adhesin

M Aspholm-Hurtig, G Dailide, M Lahmann, A Kalia… - Science, 2004 - science.org
Adherence by Helicobacter pylori increases the risk of gastric disease. Here, we report that
more than 95% of strains that bind fucosylated blood group antigen bind A, B, and O …

Global Phylogeny of Mycobacterium tuberculosis Based on Single Nucleotide Polymorphism (SNP) Analysis: Insights into Tuberculosis Evolution, Phylogenetic …

I Filliol, AS Motiwala, M Cavatore, W Qi… - Journal of …, 2006 - Am Soc Microbiol
We analyzed a global collection of Mycobacterium tuberculosis strains using 212 single
nucleotide polymorphism (SNP) markers. SNP nucleotide diversity was high (average …