Since its discovery in 2012, CRISPR Cas9 has been tried as a direct treatment approach to
correct the causative gene mutation and establish animal models in neurodegenerative …

Neurodegenerative diseases are prominent causes of pain, suffering, and death worldwide.
Traditional approaches modelling neurodegenerative diseases are deficient, and therefore …

Within the last decade, we have learned that damaged mitochondria activate many of the
same innate immune pathways that evolved to sense and respond to intracellular …

Parkinson's disease is typically characterized by the progressive loss of dopaminergic
neurons in the substantia nigra pars compacta. Many studies have been performed based …

由于帕金森病的典型病理改变是黑质致密部中多巴胺能神经元的退行性变,
许多研究都是基于补充丢失的多巴胺能神经元来治疗帕金森病. 针对细胞替代治疗的策略最初 …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, affecting 3% of individuals of> 75 years of age. The disease is relentless and …

Stem cells are immature cells that have ability to differentiate into all specific and mature
cells in body. The two main characteristics of stem cells are self-renewable and ability to …