Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic systemic
inflammation causing progressive joint damage that can lead to lifelong disability. The …

Rheumatoid arthritis (RA) is characterised by severe joint and bone damage due to
heightened autoimmune response at the articular sites. Worldwide annual incidence and …

Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Objectives To summarise, by a systematic literature review (SLR), the evidence regarding
pharmacological and non-pharmacological therapeutic strategies in difficult-to-treat …

Objectives To systematically assess the efficacy and safety of IL-17 inhibitors in patients with
active ankylosing spondylitis. Methods A systematic review of the literature was performed …

The complex crosstalk between the immune and the skeletal systems plays an
indispensable role in the maintenance of skeletal homeostasis. Various cytokines are …

Precision medicine refers to a highly individualized and personalized approach to patient
care. Pharmacogenomics is the study of how an individual's genomic profile affects their …

Rheumatoid arthritis (RA) is characterized by processive synovial hyperplasia and abnormal
proliferation of fibroblast-like synoviocytes (FLSs), and can eventually lead to progressive …

Rheumatoid arthritis (RA) is a systemic inflammatory joint disease affecting about 1% of the
population worldwide. Current treatment approaches do not ensure a cure for every patient …

Abstract Interleukin-23 (IL-23) and IL-17 are the gatekeepers of CD4+ T helper 17 (Th17)
cells where IL-23 is required for the development and expansion of Th17 cells that …