Recent advances in microwave-assisted copper-catalyzed cross-coupling reactions

Y Baqi - Catalysts, 2020 - mdpi.com
Cross-coupling reactions furnishing carbon–carbon (C–C) and carbon–heteroatom (C–X)
bond is one of the most challenging tasks in organic syntheses. The early developed …

Modern Development in Copper‐and Nickel‐Catalyzed Cross‐Coupling Reactions: Formation of Carbon‐Carbon and Carbon‐Heteroatom bonds under Microwave …

KSM Salih - Asian Journal of Organic Chemistry, 2022 - Wiley Online Library
The use of transition metals in cross‐coupling reactions has been verified as a powerful tool
in synthetic organic chemistry to access valuable pharmaceutical intermediates and …

High-throughput synthesis and optimization of ionizable lipids through A3 coupling for efficient mRNA delivery

J Li, J Hu, D Jin, H Huo, N Chen, J Lin, X Lu - Journal of …, 2024 - Springer
Background The efficacy of mRNA-based vaccines and therapies relies on lipid
nanoparticles (LNPs) as carriers to deliver mRNA into cells. The chemical structure of …

Sunlight-induced three-component synthesis of α-aminoketones: a green and sustainable pathway through an EDA complex

J Wang, Z Zhang, C Li, M Wang, J Tan, H Du… - Organic Chemistry …, 2024 - pubs.rsc.org
A sunlight-promoted three-component reaction involving aryl/alkyl glyoxal hydrates, anilines,
and 4-alkyl DHPs is described herein, which enables the synthesis of various α …

Catalysts For Propargylamines Synthesis Via A3, AHA, and KA2 Coupling-A Review

A Berrichi, R Bachir, S Bedrane - Current Organic Chemistry, 2023 - ingentaconnect.com
Different intermediates are key molecules to synthesize high-added value bioactive and
pharmacology molecules such as propargylamines may be synthesized in several ways …

Switchable Mono‐and Dipropargylation of Amino Alcohols: A Unique Property of the Iodide Anion in Controlling Ring‐Opening Alkynylation

H Feng, F Wang, L Cao… - European Journal of …, 2021 - Wiley Online Library
The application of multicomponent reactions has been recognized as the most versatile
strategy to achieve molecular diversity in organic synthesis. The reaction pathway and …

Accessing N‐Propargyl Amino Alcohols through Cu(I)‐Catalyzed A3‐Coupling/Annulation and Bi(III)‐Promoted Ring‐Opening

L Cao, P Zhou, J Hu, L Huang, H Feng - ChemistrySelect, 2022 - Wiley Online Library
An efficient one‐pot, two‐step process of N‐propargylation of amino alcohols involving in
situ protection and deprotection of the amino alcohols. This reaction is initiated by a Cu (I) …

Methanol as a C1 Source for the Synthesis of 1, 3‐Polyheterocyclic Systems

L Molteni, EM Beccalli, L Castoldi… - European Journal of …, 2023 - Wiley Online Library
A very attractive approach toward 1, 3‐polyheterocyclic systems was provided exploiting the
copper‐catalyzed reaction of aminoalcohols and diaminoalkanes, in oxidative conditions …

Sustainability and innovation of catalytic processes for the synthesis and transformation of heterocyclic systems of biological interest

L Molteni - 2024 - air.unimi.it
Functionalized heterocycles represent one of the most widespread structural motifs found in
both molecules of natural origin and in synthetic compounds exhibiting diverse activities …

Synthetic Studies Towards BML-111 Analogs

NR Saba - 2023 - duo.uio.no
Inflammasjon spiller en sentral rolle i mange kroniske sykdommer og den kan oppløses
gjennom en aktiv prosess som krever samspill mellom en stor gruppe av endogene …