SIRT7: the seventh key to unlocking the mystery of aging

U Raza, X Tang, Z Liu, B Liu - Physiological Reviews, 2024 - journals.physiology.org
Aging is a chronic yet natural physiological decline of the body. Throughout life, humans are
continuously exposed to a variety of exogenous and endogenous stresses, which engender …

Cellular stress response to extremely low‐frequency electromagnetic fields (ELF‐EMF): An explanation for controversial effects of ELF‐EMF on apoptosis

M Barati, B Darvishi, MA Javidi… - Cell …, 2021 - Wiley Online Library
Impaired apoptosis is one of the hallmarks of cancer, and almost all of the non‐surgical
approaches of eradicating tumour cells somehow promote induction of apoptosis. Indeed …

Fates and functions of RNA‐binding proteins under stress

B Goswami, S Nag, PS Ray - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
Exposure to stress activates a well‐orchestrated set of changes in gene expression
programs that allow the cell to cope with and adapt to the stress, or undergo programmed …

Identification of Key Genes and Pathways in Genotoxic Stress Induced Endothelial Dysfunction: Results of Whole Transcriptome Sequencing

M Sinitsky, A Sinitskaya, D Shishkova, A Tupikin… - Biomedicines, 2022 - mdpi.com
Atherosclerosis is a leading cause of cardiovascular morbidity and mortality worldwide.
Endothelial disfunction underlying the atherogenesis can be triggered by genotoxic stress in …

Systems Biology for Drug Target Discovery in Acute Myeloid Leukemia

S Novikova, T Tolstova, L Kurbatov… - International Journal of …, 2024 - mdpi.com
Combining new therapeutics with all-trans-retinoic acid (ATRA) could improve the efficiency
of acute myeloid leukemia (AML) treatment. Modeling the process of ATRA-induced …

Proteomic Profiling of Endothelial Cells Exposed to Mitomycin C: Key Proteins and Pathways Underlying Genotoxic Stress-Induced Endothelial Dysfunction

M Sinitsky, E Repkin, A Sinitskaya, V Markova… - International Journal of …, 2024 - mdpi.com
Mitomycin C (MMC)-induced genotoxic stress can be considered to be a novel trigger of
endothelial dysfunction and atherosclerosis—a leading cause of cardiovascular morbidity …

Genotoxin Stress and the Role of Alkaloids

V Yadav, D Vohora - Adaptation under Stressful Environments through …, 2024 - Springer
Humans are subjected to an array of external and internal stimuli during their lives, which
injure genetic material and generate somatic mutations that lead to accumulating genomic …

The Protein Response of Salt-Tolerant Zygosaccharomyces rouxii to High-Temperature Stress during the Lag Phase

N Hu, X Xiao, L Yao, X Chen, X Li - Journal of Fungi, 2024 - mdpi.com
Zygosaccharomyces rouxii used in soy sauce brewing is an osmotolerant and halotolerant
yeast, but it is not tolerant to high temperatures and the underlying mechanisms remain …

RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress

G Mohanan, R Roy, H Malka-Mahieu, S Lamba… - bioRxiv, 2022 - biorxiv.org
RGG motif-containing proteins are the second largest group of RNA-binding proteins. These
proteins have been implicated in several cellular processes. Here we identify a new role of …