Glioblastoma multiforme (GBM) is one of the most lethal forms of primary brain tumors.
Glioblastoma stem cells (GSCs) play an undeniable role in tumor development by activating …

Gene expression dictates fundamental cellular processes and its de-regulation leads to
pathological conditions. A key contributor to the fine-tuning of gene expression is Dicer, an …

Patients with hyperthyroidism are commonly diagnosed with mood disorders. Naringin,(4′,
5, 7-trihydrocyflavanone-7-O-rhamnoglucoside), a natural bioflavonoid, has many …

Oestrogen deprivation as a consequence of menopause alters the brain neuronal circuit and
results in the development of neurobehavioural symptoms later. Hormone replacement …

Cannabidiol (CBD) is a potential antidepressant agent. We examined the association
between the antidepressant effects of CBD and alterations in brain microRNAs in the …

Inhibition of fatty acid amide hydrolase (FAAH), which increases anandamide levels, has
been suggested as a potential treatment for stress-related conditions. We examined whether …

The effect and mechanism of resveratrol on depression‑like behavior in mice with
depression were investigated. A mouse model of depression was established by social …

Cerebral cortical development in mammals involves a highly complex and organized set of
events including the transition of neural stem and progenitor cells (NSCs) from proliferative …

Widespread, debilitating and often treatment-resistant, depression and other stress-related
neuropsychiatric disorders represent an urgent unmet biomedical and societal problem …

MicroRNAs (miRNAs) are non-encoding, single-stranded RNA molecules of about 22
nucleotides in length encoded by endogenous genes involved in posttranscriptional gene …