Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for hydride transfer reactions and
a substrate for sirtuins and other NAD+-consuming enzymes. The abundance of NAD+ …

The concepts, theoretical behavior and experimental applications of temporal diffusion
spectroscopy are reviewed and illustrated. Temporal diffusion spectra are obtained using …

The recent Ebola virus (EBOV) outbreak in West Africa was the largest recorded in history
with over 28,000 cases, resulting in> 11,000 deaths including> 500 healthcare workers. A …

Nanomedicines (NMs) offer new solutions for cancer diagnosis and therapy. However,
extension of progression-free interval and overall survival time achieved by Food and Drug …

Dendritic spines, the postsynaptic compartments of excitatory neurotransmission, have
different shapes classified from 'stubby'to 'mushroom-like'. Whereas mushroom spines are …

Glutathione plays many important roles in biological processes; however, the dynamic
changes of glutathione concentrations in living cells remain largely unknown. Here, we …

The SARS‐CoV‐2 main protease (Mpro) cleaves along the two viral polypeptides to release
non‐structural proteins required for viral replication. MPro is an attractive target for antiviral …

Oocytes undergo a range of complex processes via oogenesis, maturation, fertilization, and
early embryonic development, eventually giving rise to a fully functioning organism. To …

Because of cellular heterogeneity, the analysis of endogenous molecules from single cells is
of significant interest and has major implications. While micromanipulation or cell sorting …

In eukaryotes, the cell volume is observed to be strongly correlated with the nuclear volume.
The slope of this correlation depends on the cell type, growth condition, and the physical …