Potassium channels are transmembrane proteins that selectively facilitate the flow of
potassium ions down an electrochemical gradient. These molecules have been studied in …

Two-pore domain K+(K 2P) channels give rise to leak (also called background) K+ currents.
The well-known role of background K+ currents is to stabilize the negative resting …

The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Potassium (K+) channels are highly regulated membrane proteins that control the potassium
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …

In this review, we summarize our knowledge about mitochondrial potassium channels, with
a special focus on unanswered questions in this field. The following potassium channels …

Mitochondria are vital to life and provide biological energy for other organelles and cell
physiological processes. On the mitochondrial double layer membrane, there are a variety of …

Potassium channels are a diverse group of pore-forming transmembrane proteins that
selectively facilitate potassium flow through an electrochemical gradient. They participate in …

Pharmacological targeting of mitochondrial ion channels is emerging as a promising
approach to eliminate cancer cells; as most of these channels are differentially expressed …

Several types of channels play a role in the maintenance of ion homeostasis in subcellular
organelles including endoplasmatic reticulum, nucleus, lysosome, endosome, and …

Mitochondrial potassium channels are believed to contribute to cytoprotection of injured
cardiac and neuronal tissues. The following potassium channels have been described in the …