The gem-difluoroalkenes and related compounds have gained much attention from the
organic synthetic community due to their widespread applications as versatile fluorinated …

The activation and transformation of organic chemical bonds is a fundamental scientific
problem. In the past several decades, C–S bond cleavage for the construction of C–C and C …

Recent protocols and reactions for catalytic radical perfluoroalkylations will be described.
The production of perfluoroalkyl radicals (RF= C n F2 n+ 1, n≥ 2), which effect both addition …

A new olefination protocol for transition-metal-free cross-coupling of two carbene fragments
arising from two different sources, namely, a nonfluorinated carbene fragment resulting from …

We report a NiH‐catalyzed migratory defluorinative coupling between two electronically
differentiated olefins. A broad range of unactivated donor olefins can be joined directly to …

In this protocol, we report an allylic defluorinative reductive cross-coupling reaction for C–C
bond formation. Under the Ni-catalysis the challenging C (sp3)–F bond cleavage of …

We report the first iron-catalyzed difluoromethylation of arylzincs with difluoromethyl 2-
pyridyl sulfone via selective C–S bond cleavage. This method employs the readily available …

Driven by the continuous demand for optically active fluoro-containing molecules from the
chemical society, the field of fluorochemistry has emerged as a hot topic recently. While …

A copper-catalyzed system has been introduced for the enantioselective defluoroalkylation
of linear 1-(trifluoromethyl) alkenes through C–F activation to synthesize various gem …

A visible-light-promoted redox neutral γ, γ-difluoroallylation of cycloketone oxime ethers with
trifluoromethyl alkenes through C–C and C–F bond cleavage has been achieved, which …