[HTML][HTML] Leveraging genetic correlation structure to target discrete signaling mechanisms across metabolic tissues

M Zhou, C Van, J Molendijk, IYY Chang, C Johnson… - Elife, 2023 - elifesciences.org
Inter-organ communication is a vital process to maintain physiologic homeostasis, and its
dysregulation contributes to many human diseases. Beginning with the discovery of insulin …

MultiCens: Multilayer network centrality measures to uncover molecular mediators of tissue-tissue communication

T Kumar, R Sethuraman, S Mitra… - PLOS Computational …, 2023 - journals.plos.org
With the evolution of multicellularity, communication among cells in different tissues and
organs became pivotal to life. Molecular basis of such communication has long been …

Leveraging inter-individual transcriptional correlation structure to infer discrete signaling mechanisms across metabolic tissues

M Zhou, I Tamburini, C Van, J Molendijk, CM Nguyen… - Elife, 2024 - elifesciences.org
Inter-organ communication is a vital process to maintain physiologic homeostasis, and its
dysregulation contributes to many human diseases. Given that circulating bioactive factors …

[PDF][PDF] The study of chemical reactions in the human body through the use of hormones

AA Aldhalemi, QR Lahhob - International Journal of Advanced …, 2024 - researchgate.net
Endocrinology explores the exquisite complex his fabric of the human frame, which boast
with the symphony of hormones, is a messenger orchestra. During this exploration the …

NeuroClustr: Empowering Biomedical Text Clustering with Neuro-Symbolic Intelligence

F Alam, K Mahmood… - … Joint Conference on …, 2023 - openreview.net
The exponential growth of biomedical unstructured data being generated every day has
made it increasingly challenging to accurately cluster them and extract meaningful insights …

Using genetic variation to discover novel factors in cross-tissue signaling

C Van - 2024 - search.proquest.com
The study of cross-tissue communication has become more significant to the study of
metabolic regulation and physiological homeostasis, from the level of fundamental signaling …

[PDF][PDF] Rich Graph Structures: Algorithms and Applications

T Kumar - 2023 - cse.iitm.ac.in
In this chapter, we explore multilayer networks in the context of different coupling schemes
and understand the applicability of various centrality measures to these networks. Centrality …