Nucleic acid-based wearable and implantable electrochemical sensors

C Ye, H Lukas, M Wang, Y Lee, W Gao - Chemical Society Reviews, 2024 - pubs.rsc.org
The rapid advancements in nucleic acid-based electrochemical sensors for implantable and
wearable applications have marked a significant leap forward in the domain of personal …

Real-Time, In Vivo Molecular Monitoring Using Electrochemical Aptamer Based Sensors: Opportunities and Challenges

AM Downs, KW Plaxco - ACS sensors, 2022 - ACS Publications
The continuous, real-time measurement of specific molecules in situ in the body would
greatly improve our ability to understand, diagnose, and treat disease. The vast majority of …

Wearable microneedle-based electrochemical aptamer biosensing for precision dosing of drugs with narrow therapeutic windows

S Lin, X Cheng, J Zhu, B Wang, D Jelinek, Y Zhao… - Science …, 2022 - science.org
Therapeutic drug monitoring is essential for dosing pharmaceuticals with narrow therapeutic
windows. Nevertheless, standard methods are imprecise and involve invasive/resource …

Microneedle aptamer-based sensors for continuous, real-time therapeutic drug monitoring

Y Wu, F Tehrani, H Teymourian, J Mack… - Analytical …, 2022 - ACS Publications
The ability to continuously monitor the concentration of specific molecules in the body is a
long-sought goal of biomedical research. For this purpose, interstitial fluid (ISF) was …

Rapid and efficient detection of the SARS-CoV-2 spike protein using an electrochemical aptamer-based sensor

A Idili, C Parolo, R Alvarez-Diduk, A Merkoçi - ACS sensors, 2021 - ACS Publications
The availability of sensors able to rapidly detect SARS-CoV-2 directly in biological fluids in a
single step would allow performing massive diagnostic testing to track in real time and …

An ultrasensitive CRISPR/Cas12a based electrochemical biosensor for Listeria monocytogenes detection

F Li, Q Ye, M Chen, B Zhou, J Zhang, R Pang… - Biosensors and …, 2021 - Elsevier
Listeria monocytogenes is an important foodborne pathogen that can cause listeriosis with
high patient mortality. Accordingly, it is necessary to develop a L. monocytogenes detection …

A megatrend challenging analytical chemistry: biosensor and chemosensor concepts ready for the internet of things

M Mayer, AJ Baeumner - Chemical reviews, 2019 - ACS Publications
The Internet of Things (IoT) is a megatrend that cuts across all scientific and engineering
disciplines and establishes an integrating technical evolution to improve production …

Electrochemical aptamer-based sensors for improved therapeutic drug monitoring and high-precision, feedback-controlled drug delivery

P Dauphin-Ducharme, K Yang, N Arroyo-Currás… - ACS …, 2019 - ACS Publications
The electrochemical aptamer-based (E-AB) sensing platform appears to be a convenient
(rapid, single-step, and calibration-free) and modular approach to measure concentrations …

Surpassing the detection limit and accuracy of the electrochemical DNA sensor through the application of CRISPR Cas systems

W Xu, T Jin, Y Dai, CC Liu - Biosensors and Bioelectronics, 2020 - Elsevier
Robust developments of personalized medicine for next-generation healthcare highlight the
need for sensitive and accurate point-of-care platforms for quantification of disease …

Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing

X Ji, X Lin, J Rivnay - Nature communications, 2023 - nature.com
Electrochemical aptamer-based sensors are typically deployed as individual, passive,
surface-functionalized electrodes, but they exhibit limited sensitivity especially when the …