Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Strategies for bone regeneration: from graft to tissue engineering

G Battafarano, M Rossi, V De Martino… - International journal of …, 2021 - mdpi.com
Bone is a regenerative organ characterized by self-renewal ability. Indeed, it is a very
dynamic tissue subjected to continuous remodeling in order to preserve its structure and …

Bioorthogonal PROTAC prodrugs enabled by on-target activation

M Chang, F Gao, D Pontigon, G Gnawali… - Journal of the …, 2023 - ACS Publications
Although proteolysis targeting chimeras (PROTACs) have become promising therapeutic
modalities, important concerns exist about the potential toxicity of the approach owing to …

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

Self-assembling peptide scaffolds in the clinic

F Gelain, Z Luo, M Rioult, S Zhang - NPJ Regenerative medicine, 2021 - nature.com
Well-defined scaffold hydrogels made of self-assembling peptides have found their way into
clinical products. By examining the properties and applications of two self-assembling …

Electrospun hybrid nanofibers: Fabrication, characterization, and biomedical applications

B Abadi, N Goshtasbi, S Bolourian, J Tahsili… - … in Bioengineering and …, 2022 - frontiersin.org
Nanotechnology is one of the most promising technologies available today, holding
tremendous potential for biomedical and healthcare applications. In this field, there is an …

Recent advances in the surface functionalization of PLGA-based nanomedicines

MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …

Function and mechanism of RGD in bone and cartilage tissue engineering

M Yang, ZC Zhang, Y Liu, YR Chen… - … in bioengineering and …, 2021 - frontiersin.org
Bone and cartilage injury is common, tissue engineered scaffolds are potential means to
repair. Because most of the scaffold materials used in bone and cartilage tissue engineering …

Peptides as therapeutic agents: challenges and opportunities in the green transition era

G Rossino, E Marchese, G Galli, F Verde, M Finizio… - Molecules, 2023 - mdpi.com
Peptides are at the cutting edge of contemporary research for new potent, selective, and
safe therapeutical agents. Their rise has reshaped the pharmaceutical landscape, providing …

Design and assessment of biodegradable macroporous cryogels as advanced tissue engineering and drug carrying materials

IN Savina, M Zoughaib, AA Yergeshov - Gels, 2021 - mdpi.com
Cryogels obtained by the cryotropic gelation process are macroporous hydrogels with a well-
developed system of interconnected pores and shape memory. There have been significant …