HPLC is established as a fast convenient analytical technology for characterizing the content
of empty and full capsids in purified samples containing adeno-associated virus (AAV). UV …

The disaccharide trehalose is accumulated in the cytoplasm of some organisms in response
to harsh environmental conditions. Trehalose biosynthesis and accumulation are important …

Adeno-associated virus (AAV) is the leading platform for in vivo gene therapy to treat
numerous genetic diseases. Comprehensive analysis of the AAV particles is essential to …

The nucleotide-binding domain (N-domain) of the Na+, K+-ATPase (NKA) is
physicochemically characterized by a high content of Glu and Asp residues, resulting in a …

Lactate dehydrogenase (LDH) catalyzes the reduction of pyruvate to lactate by using NADH.
LDH kinetics has been proposed to be dependent on the dynamics of a loop over the active …

Human glucokinase (GCK) is the prototypic example of an emerging class of proteins with
allosteric-like behavior that originates from intrinsic polypeptide dynamics. High-resolution …

The purpose of the present study was to evaluate de influence of protein–sugar
complexation on the stability and functionality of C-reactive protein, after exposure to …

While biomedical investigation has greatly advanced, investigators have lost touch with and
inadvertently corrupted significant nomenclature at the foundation of their science …

The sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) is a P-type ATPase that has been
crystallized in various conformations. Detailed functional information may nonetheless be …

The hexokinase (HK) family of enzymes catalyze the conversion of glucose to glucose 6-
phosphate in a process that is utilized for energy production in most organisms. Hexokinase …