Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment
M Kar, KEE Johnson, A Vanderheiden, EJ Elrod… - Science …, 2024 - science.org
SARS-CoV-2 infection induces the generation of virus-specific CD4+ and CD8+ effector and
memory T cells. However, the contribution of T cells in controlling SARS-CoV-2 during …
memory T cells. However, the contribution of T cells in controlling SARS-CoV-2 during …
ACE2-dependent and-independent SARS-CoV-2 entries dictate viral replication and inflammatory response during infection
Excessive inflammation is the primary cause of mortality in patients with severe COVID-19,
yet the underlying mechanisms remain poorly understood. Our study reveals that ACE2 …
yet the underlying mechanisms remain poorly understood. Our study reveals that ACE2 …
The surveillance of viral infections by the unconventional Type I NKT cell
V Rajashekar, L Stern, CF Almeida… - Frontiers in …, 2024 - frontiersin.org
Type I NKT cells, also known as Invariant Natural Killer T (iNKT) cells, are a subpopulation of
unconventional, innate-like T (ILT) cells which can proficiently influence downstream …
unconventional, innate-like T (ILT) cells which can proficiently influence downstream …
A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome
TC Hammond, MA Purbhoo, S Kadel, J Ritz… - Nature …, 2024 - nature.com
Invariant natural killer T (iNKT) cells, a unique T cell population, lend themselves for use as
adoptive therapy due to diverse roles in orchestrating immune responses. Originally …
adoptive therapy due to diverse roles in orchestrating immune responses. Originally …
Varicella zoster virus downregulates expression of the nonclassical antigen presentation molecule CD1d
R Traves, T Opadchy, B Slobedman… - The Journal of …, 2024 - academic.oup.com
Background The nonclassical antigen presentation molecule CD1d presents lipid antigens
to invariant natural killer T (iNKT) cells. Activation of these cells triggers a rapid cytokine …
to invariant natural killer T (iNKT) cells. Activation of these cells triggers a rapid cytokine …
SARS‐CoV‐2 induces blood‐brain barrier and choroid plexus barrier impairments and vascular inflammation in mice
H Qiao, X Deng, L Qiu, Y Qu, Y Chiu… - Journal of medical …, 2024 - Wiley Online Library
The coronavirus disease of 2019 (COVID‐19) pandemic has led to more than 700 million
confirmed cases and nearly 7 million deaths. Although severe acute respiratory syndrome …
confirmed cases and nearly 7 million deaths. Although severe acute respiratory syndrome …
Natural Killer T Cell Diversity and Immunotherapy
EI Tognarelli, C Gutiérrez-Vera, PA Palacios… - Cancers, 2023 - mdpi.com
Simple Summary Cell-based oncotherapies are gaining considerable terrain in the last
years thanks to the development of safe and promising treatments against cancer. A better …
years thanks to the development of safe and promising treatments against cancer. A better …