Microscopic marvels: Decoding the role of micropeptides in innate immunity
The innate immune response is under selection pressures from changing environments and
pathogens. While sequence evolution can be studied by comparing rates of amino acid …
pathogens. While sequence evolution can be studied by comparing rates of amino acid …
Toward atomistic models of intact severe acute respiratory syndrome coronavirus 2 via Martini coarse‐grained molecular dynamics simulations
D Wang, J Li, L Wang, Y Cao, B Kang… - Quantitative …, 2023 - Wiley Online Library
The causative pathogen of coronavirus disease 2019 (COVID‐19), severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), is an enveloped virus assembled by a lipid …
syndrome coronavirus 2 (SARS‐CoV‐2), is an enveloped virus assembled by a lipid …
Exploring the alternative conformation of a known protein structure based on contact map prediction
The rapid development of deep learning-based methods has considerably advanced the
field of protein structure prediction. The accuracy of predicting the 3D structures of simple …
field of protein structure prediction. The accuracy of predicting the 3D structures of simple …
Three-Dimensional Interaction Homology: Deconstructing Residue–Residue and Residue–Lipid Interactions in Membrane Proteins
GE Kellogg - Molecules, 2024 - mdpi.com
A method is described to deconstruct the network of hydropathic interactions within and
between a protein's sidechain and its environment into residue-based three-dimensional …
between a protein's sidechain and its environment into residue-based three-dimensional …
Influence of the extracellular domain size on the dynamic behavior of membrane proteins
The dynamic behavior of plasma membrane proteins mediates various cellular processes
such as cellular motility, communication, and signaling. It is widely accepted that the …
such as cellular motility, communication, and signaling. It is widely accepted that the …
Molecular Identification and In Silico Protein Analysis of a Novel BCOR-CLGN Gene Fusion in Intrathoracic BCOR-Rearranged Sarcoma
YC Chang Chien, K Madarász, SL Csoma, JA Mótyán… - Cancers, 2023 - mdpi.com
Simple Summary BCOR (BCL6 corepressor)-rearranged sarcoma (BRS) is a rare sarcoma
entity with a predominantly BCOR-CCNB3 fusion. In this paper, we present an index case of …
entity with a predominantly BCOR-CCNB3 fusion. In this paper, we present an index case of …
ProtRAP: Predicting lipid accessibility together with solvent accessibility of proteins in one run
Solvent accessibility has been extensively used to characterize and predict the chemical
properties of the surface residues of soluble proteins. However, there is not yet a widely …
properties of the surface residues of soluble proteins. However, there is not yet a widely …
Rapid Prediction of Lipid Interaction Sites on Pleckstrin Homology Domains Using Deep Graph Neural Networks and Molecular Dynamics Simulations
KIP Le Huray, F Sobott, H Wang, AC Kalli - bioRxiv, 2023 - biorxiv.org
Interactions between membrane proteins and specific lipid molecules play a major role in
cellular biology, but characterizing these interactions can be challenging due to the …
cellular biology, but characterizing these interactions can be challenging due to the …
Identification et caractérisation de formes rares de surcharge en fer: analyses structurales et fonctionnelles de la ferroportine et étude de la régulation à distance du …
K Uguen - 2022 - theses.hal.science
La ferroportine (FPN1) est le seul exportateur de fer connu chez les mammifères. Cette
protéine de 12 domaines transmembranaires fait partie de la famille des transporteurs MFS …
protéine de 12 domaines transmembranaires fait partie de la famille des transporteurs MFS …