Advances in genomics have deepened our understanding of the biology of acute
lymphoblastic leukemia (ALL), defined novel molecular leukemia subtypes, discovered new …

Transcription factors (TFs) play a critical role as key mediators of a multitude of
developmental pathways, with highly regulated and tightly organized networks crucial for …

Background Recurrent genetic lesions provide basis for risk assessment in pediatric acute
lymphoblastic leukemia (ALL). However, current prognostic classifiers rely on a limited …

Background Recurrent genetic alterations contributing to leukemogenesis have been
identified in pediatric B-cell Acute Lymphoblastic Leukemia (B-ALL), and some are useful for …

Introduction Acute lymphoblastic leukemia (ALL) is the most common childhood cancer in
the world, which is associated with a wide spectrum of factors that play an important role in …

Acute lymphoblastic leukemia (ALL) is a malignancy associated with altered lymphoid
precursor hyperplasia and accompanied with different genetic mutations. Few studies have …

Background Refining risk stratification to avoid very early relapses (VER) in Mexican
patients with B-lineage acute lymphoblastic leukemia (B-ALL) could lead to better survival …

Minimal residual disease (MRD) describes the remaining amount of cancerous cells among
healthy cells during or after therapy. The monitoring of MRD over time provides valuable …

Las deleciones de IZF1 y algunos otros genes se han asociado con mal pronóstico. Este
estudio tiene como objetivo describir la frecuencia de deleciones de IKZF1, CDKN2A …

Este trabajo se llevó a cabo en la Unidad de Bioquímica y Biología Molecular de Plantas del
Centro de Investigación Científica de Yucatán, y forma parte del proyecto titulado …