Renal cancer: signaling pathways and advances in targeted therapies

A Jiang, J Li, Z He, Y Liu, K Qiao, Y Fang, L Qu… - MedComm, 2024 - Wiley Online Library
Renal cancer is a highlyheterogeneous malignancy characterized by rising global incidence
and mortalityrates. The complex interplay and dysregulation of multiple signaling pathways …

Impacts of preparation technologies on biological activities of edible mushroom polysaccharides–novel insights for personalized nutrition achievement

G Ma, X Li, Q Tao, S Ma, H Du, Q Hu… - Critical Reviews in Food …, 2024 - Taylor & Francis
Edible mushroom polysaccharides (EMPs) as a natural macromolecular carbohydrate have
a very complex structure and composition. EMPs are considered ideal candidates for …

[HTML][HTML] Apolipoprotein-L1 (APOL1): From Sleeping Sickness to Kidney Disease

E Pays - Cells, 2024 - mdpi.com
Apolipoprotein-L1 (APOL1) is a membrane-interacting protein induced by inflammation,
which confers human resistance to infection by African trypanosomes. APOL1 kills …

[HTML][HTML] Non-coding RNAs secreted by renal cancer include piR_004153 that promotes migration of mesenchymal stromal cells

J Bogusławska, M Grzanka… - … and Signaling: CCS, 2025 - pmc.ncbi.nlm.nih.gov
Background Renal cell cancer (RCC) is the most common and highly malignant subtype of
kidney cancer. Mesenchymal stromal cells (MSCs) are components of tumor …

[HTML][HTML] Apolipoprotein-L Functions in Membrane Remodeling

E Pays - Cells, 2024 - mdpi.com
The mammalian Apolipoprotein-L families (APOLs) contain several isoforms of membrane-
interacting proteins, some of which are involved in the control of membrane dynamics (traffic …

Immunotherapy of Clear-Cell Renal-Cell Carcinoma

S Grigolo, L Filgueira - Cancers, 2024 - mdpi.com
Simple Summary Immunotherapeutic synergy represents the cornerstone of the treatment
intended for patients with clear-cell renal-cell carcinoma. In most cases, this type of cancer …

[HTML][HTML] Signaling Pathways in Clear Cell Renal Cell Carcinoma and Candidate Drugs Unveiled through Transcriptomic Network Analysis of Hub Genes

KS Suratos, MA Orda, PW Tsai, LL Tayo - Applied Sciences, 2024 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is a type of kidney cancer. It advances quickly and
often metastasizes, making the prognosis for patients challenging. This study used weighted …

Monotropein attenuates renal cell carcinoma cell progression and M2 macrophage polarization by weakening NF-κB

H Qiu, F Liu, M Qiu, J Yang, X Peng - International Urology and …, 2025 - Springer
Purpose The study aimed to investigate the effect and mechanism of monotropein on renal
cell carcinoma (RCC). Methods After monotropein and NF-κB receptor activator (RANKL) …

Impact of neoadjuvant therapy on prognosis in renal cell carcinoma with inferior vena cava thrombus

T Hara, K Suzuki, Y Okamura, H Ueki, Y Bando… - … Oncology: Seminars and …, 2024 - Elsevier
Background The standard treatment for non-metastatic renal cell carcinoma (RCC) with
inferior vena cava (IVC) thrombus is complete surgical resection; however, this procedure is …

HECTD2/TNFAIP1 Axis Regulating the p38/JNK Pathway to Promote an Inflammatory Response in Renal Cell Carcinoma Cells

D Lv, Y Chen, L Tang, Y Tian, D Ren, N Jian, T Shen - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: The underlying processes of renal cell carcinoma (RCC), one of the
deadliest malignancies of the urinary system, are still poorly understood. HECT domain E3 …