Following the discovery of leptin in 1994, the scientific and clinical communities have held
great hope that manipulation of the leptin axis may lead to the successful treatment of …

There has been great interest in dry matter intake regulation in lactating dairy cattle to
enhance performance and improve animal health and welfare. Predicting voluntary dry …

Leptin, the protein product of the obese (ob or Lep) gene, is a hormone synthesized by
adipocytes that signals available energy reserves to the brain, and thereby influences …

To achieve energy balance and maintain a constant BW, changes in feed intake and energy
expenditure must be coordinated and tightly regulated. This may not hold true for some …

Leptin is the adipocyte-specific product of the ob gene. Expression of leptin in fully fed
animals reflects adipocyte size and body-fat mass. Leptin signals the status of body energy …

Intensive selection by poultry breeders over many generations for economically important
production traits such as growth rate and meat production has been accompanied by …

This paper reviews data on leptin gene expression in adipose tissue (AT) and mammary
gland of adult ruminants, as well as on plasma leptin variations, according to genetic …

Leptin is a key factor in the regulation of food intake and is an important factor in the
pathophysiology of obesity. However, more than a decade after the discovery of leptin in …

In this sweeping exploration of the relatively recent obesity epidemic, Michael L. Power and
Jay Schulkin probe evolutionary biology, history, physiology, and medical science to …

The production of peptide hormones by skeletal muscle tissue is a promising area of gene
therapy. Skeletal muscle myogenesis can be induced in vitro, resulting in the fusion of …