Mast cells and their mediators have been implicated in the pathogenesis of asthma and
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …

Inflammation is indispensable for host homeostasis against invading pathogens and efficient
wound healing upon tissue malfunction and has to be tightly controlled by various …

Adipose tissue (AT) has previously been identified as an extra-medullary reservoir for
normal hematopoietic stem cells (HSCs) and may promote tumor development. Here, we …

Background aims Adipose tissue is a rich and very convenient source of cells for
regenerative medicine therapeutic approaches. However, a characterization of the …

During an infection, the body increases the output of mature immune cells in order to fight off
the pathogen. Despite convincing evidence that hematopoietic stem and progenitor cells …

Clinical use of adipose-derived stem cells (ASCs) for a variety of indications is rapidly
expanding in medicine. Most commonly, ASCs are isolated at the point of care from …

Emerging evidence suggests that increases in activated T cell populations in adipose tissue
may contribute toward obesity-associated metabolic syndrome. The present study …

The explosion of new information in recent years on the origin of macrophages in the steady-
state and in the context of inflammation has opened up numerous new avenues of …

In the past decade, adipose tissue became a highly interesting source of adult stem cells for
plastic surgery and regenerative medicine. The isolated stromal vascular fraction (SVF) is a …

Abstract Acute Myeloid Leukaemia (AML) is a genetically, biologically and clinically
heterogeneous set of diseases, which are characterised by an increased growth of …