Second messengers and their importance for novel drug treatments of patients with bipolar disorder

G Sani, GD Kotzalidis, F Fiasche… - … Review of Psychiatry, 2022 - Taylor & Francis
Second messenger systems, like the cyclic nucleotide, glycogen synthase kinase-3β,
phosphoinositide, and arachidonic acid cascades, are involved in bipolar disorder (BD). We …

Ca 2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses

S Zhai, S Otsuka, J Xu, VRJ Clarke, T Tkatch… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Long-term synaptic plasticity at glutamatergic synapses on striatal spiny projection neurons
(SPNs) is central to learning goal-directed behaviors and habits. Although considerable …

[HTML][HTML] Relative Molecular Similarity in Compound Structures Modulating Neurodegenerative Apoptosis

WR Williams - Journal of Biosciences and Medicines, 2023 - scirp.org
Neurodegeneration is attributable to metabolic disturbances in the various cell types
responsible for this condition, in respect of glucose utilisation and dysfunctional …

FRET-based cGMP Imaging in the Nervous System

S Peters - 2024 - tobias-lib.ub.uni-tuebingen.de
Impaired cyclic 3'5'guanosine monophosphate (cGMP) signaling has been linked to several
neurological disorders, including inaccurate axon formation and pathfinding. It is well known …