Abstract Follicular helper T (T FH) cells participate in humoral responses providing selection
signals to germinal center B cells. Recently, expression of CXCR5, PD-1, and the …

Germinal Centres (GCs) are transient structures in secondary lymphoid organs, where
affinity maturation of B cells takes place following an infection. While GCs are responsible for …

Germinal centres are receiving renewed attention following recent intravital multi-photon
imaging studies. These data have shed new light on longstanding questions about the …

Ebola virus (EBOV) infection causes a high death toll, killing a high proportion of EBOV-
infected patients within 7 days. Comprehensive data on EBOV infection are fragmented …

Immunization with a T cell-dependent Ag leads to the formation of several hundred germinal
centers (GCs) within secondary lymphoid organs, a key process in the maturation of the …

Germinal centers (GC) are large aggregates of proliferating B lymphocytes within follicles of
lymphoid tissue that form during adaptive immune responses. GCs are the source of long …

Germinal centers (GCs) are transient anatomical microenvironments where antibody affinity
maturation and memory B cells generation takes place. In the past, models of Germinal …

DAP-related apoptotic kinase-2 (DRAK2), a death-associated protein kinase family member,
is highly expressed in B and T lymphocytes in the human and the mouse. To determine …

This paper describes a novel software algorithm, called constrained Sequential Monte Carlo
(SMC) clusters, for tracking a large collection of individual cells from intra-vital two-photon …

We analyze the interactions between division, mutation and selection in a simplified
evolutionary model, assuming that the population observed can be classified into fitness …