[PDF][PDF] Meta‐analysis of the influence of I148M variant of patatin‐like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological …

S Sookoian, CJ Pirola - Hepatology, 2011 - Wiley Online Library
Our objective was to estimate the strength of the effect of the I148M (rs738409 C/G) patatin‐
like phospholipase domain containing 3 (PNPLA3) variant on nonalcoholic fatty liver …

[PDF][PDF] Nonalcoholic fatty liver disease in adolescents and young adults: the next frontier in the epidemic

I Doycheva, KD Watt, N Alkhouri - Hepatology, 2017 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a significant health burden in adolescents and
young adults (AYAs) which has substantially risen in prevalence over the last decades. The …

Genetic predisposition in NAFLD and NASH: impact on severity of liver disease and response to treatment

P Dongiovanni, QM Anstee… - Current pharmaceutical …, 2013 - ingentaconnect.com
Liver fat deposition related to systemic insulin resistance defines non-alcoholic fatty liver
disease (NAFLD) which, when associated with oxidative hepatocellular damage …

ISMRM workshop on fat–water separation: insights, applications and progress in MRI

HH Hu, P Börnert, D Hernando… - Magnetic resonance …, 2012 - Wiley Online Library
Approximately 130 attendees convened on February 19–22, 2012 for the first ISMRM‐
sponsored workshop on water–fat imaging. The motivation to host this meeting was driven …

Association between PNPLA3 rs738409 polymorphism and nonalcoholic fatty liver disease (NAFLD) susceptibility and severity: A meta-analysis

G Dai, P Liu, X Li, X Zhou, S He - Medicine, 2019 - journals.lww.com
Objective: This meta-analysis is to investigate the relationship between the patatin-like
phospholipase domain containing 3 (PNPLA3) rs738409 polymorphism and the …

[HTML][HTML] A 360-degree overview of paediatric NAFLD: recent insights

V Nobili, G Svegliati-Baroni, A Alisi, L Miele… - Journal of …, 2013 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a multi-faceted disorder, which ranges from
simple steatosis to non-alcoholic steatohepatitis (NASH) with/without fibrosis. The effects of …

Association between patatin-like phospholipase domain containing 3 gene (PNPLA3) polymorphisms and nonalcoholic fatty liver disease: a HuGE review and meta …

R Xu, A Tao, S Zhang, Y Deng, G Chen - Scientific reports, 2015 - nature.com
We conducted a meta-analysis to assess the association between patatin-like
phospholipase domain-containing 3 (PNPLA3) rs738409 polymorphism and nonalcoholic …

[HTML][HTML] Hepatic fatty acid trafficking: multiple forks in the road

DG Mashek - Advances in nutrition, 2013 - Elsevier
The liver plays a unique, central role in regulating lipid metabolism. In addition to influencing
hepatic function and disease, changes in specific pathways of fatty acid (FA) metabolism …

[HTML][HTML] Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar …

JN Davis, KA Leˆ, RW Walker, S Vikman… - The American journal of …, 2010 - Elsevier
Background: Recently, a genetic variant (rs738409; C→ G) of the PNPLA3 gene was
identified to be associated with increased hepatic fat deposition, and the effect was more …

Non-alcoholic fatty liver disease in obese youth with insulin resistance and type 2 diabetes

S Scapaticci, E D'Adamo, A Mohn, F Chiarelli… - Frontiers in …, 2021 - frontiersin.org
Currently, Non-Alcoholic Fatty Liver Disease (NAFLD) is the most prevalent form of chronic
liver disease in children and adolescents worldwide. Simultaneously to the epidemic …