Linking gut microbiome and lipid metabolism: moving beyond associations

S Lamichhane, P Sen, MA Alves, HC Ribeiro… - Metabolites, 2021 - mdpi.com
Various studies aiming to elucidate the role of the gut microbiome-metabolome co-axis in
health and disease have primarily focused on water-soluble polar metabolites, whilst non …

Recent developments along the analytical process for metabolomics workflows

C Gonzalez-Riano, D Dudzik, A Garcia… - Analytical …, 2019 - ACS Publications
We are in the midst of a shift in biological research paradigms from reductionist
methodologies that generate a hypothesis and rigorously and quantitatively measure the …

HMDB 5.0: the human metabolome database for 2022

DS Wishart, AC Guo, E Oler, F Wang… - Nucleic acids …, 2022 - academic.oup.com
Abstract The Human Metabolome Database or HMDB (https://hmdb. ca) has been providing
comprehensive reference information about human metabolites and their associated …

Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer

P Kreuzaler, P Inglese, A Ghanate, E Gjelaj, V Wu… - Nature …, 2023 - nature.com
Tumors are intrinsically heterogeneous and it is well established that this directs their
evolution, hinders their classification and frustrates therapy,–. Consequently, spatially …

ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies

C Lorenzo, P Delgado, CE Busse, A Sanz-Bravo… - Nature, 2021 - nature.com
Cardiovascular disease (CVD) is the leading cause of mortality in the world, with most CVD-
related deaths resulting from myocardial infarction or stroke. The main underlying cause of …

Omics technologies in allergy and asthma research: An EAACI position paper

U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …

Specialized phenolic compounds in seeds: Structures, functions, and regulations

M Corso, F Perreau, G Mouille, L Lepiniec - Plant Science, 2020 - Elsevier
Plants produce a huge diversity of specialized metabolites (SM) throughout their life cycle
that play important physiological and ecological functions. SM can protect plants and seeds …

Prognostic biomarkers of Parkinson's disease in the Spanish EPIC cohort: A multiplatform metabolomics approach

C Gonzalez-Riano, J Saiz, C Barbas… - npj Parkinson's …, 2021 - nature.com
The lack of knowledge about the onset and progression of Parkinson's disease (PD)
hampers its early diagnosis and treatment. Metabolomics might shed light on the PD imprint …

Effect of providing citrus pulp-integrated diet on fecal microbiota and serum and fecal metabolome shifts in crossbred pigs

D Belloumi, S Calvet, MI Roca, P Ferrer… - Scientific Reports, 2023 - nature.com
The study aimed to assess the impact of dehydrated citrus pulp (DCP) on growth
performance, fecal characteristics, fecal bacterial composition (based on 16S rRNA …

A genomic toolkit for the mechanistic dissection of intractable human gut bacteria

JE Bisanz, P Soto-Perez, C Noecker, AA Aksenov… - Cell Host & Microbe, 2020 - cell.com
Despite the remarkable microbial diversity found within humans, our ability to link genes to
phenotypes is based upon a handful of model microorganisms. We report a comparative …