Advances in microfluidics for single red blood cell analysis

GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Advanced optical tweezers on cell manipulation and analysis

S Hu, J Ye, Y Zhao, C Zhu - The European Physical Journal Plus, 2022 - Springer
Optical tweezers (OTs), which generate a variety of fascinating beam patterns, allow
biologists to uncover the natural secrets of human life at single-cell level. Due to its gentle …

Normal saline-induced deoxygenation of red blood cells probed by optical tweezers combined with the micro-Raman technique

J Lukose, N Mithun, G Mohan, S Shastry, S Chidangil - RSC advances, 2019 - pubs.rsc.org
The use of normal saline for washing red blood cells and treating critically ill patients is a
regular medical practice in hospital settings. An optical tweezer in combination with Raman …

Development of a flow cell based Raman spectroscopy technique to overcome photodegradation in human blood

B Hansson, CH Allen, S Qutob, B Behr… - Biomedical optics …, 2019 - opg.optica.org
Raman spectroscopy of blood offers significant potential for label-free diagnostics of
disease. However, current techniques are limited by the use of low laser power to avoid …

The effects of short term hyperglycemia on human red blood cells studied using Raman spectroscopy and optical trap

Y Singh, A Chowdhury, R Dasgupta… - European Biophysics …, 2021 - Springer
Management of postprandial hyperglycemia is important for preventing severe
complications like cardiovascular disease in diabetes patients. The associated glycemic …

Plasmodium perforin-like protein pores on the host cell membrane contribute in its multistage growth and erythrocyte senescence

S Garg, A Shivappagowdar, RS Hada… - Frontiers in Cellular …, 2020 - frontiersin.org
The pore forming Plasmodium Perforin Like Proteins (PPLP), expressed in all stages of the
parasite life cycle are critical for completion of the parasite life cycle. The high sequence …

Advancing Transfusion Medicine through Raman Tweezers Spectroscopy: A Review of Recent Progress and Future Perspectives

M Nelliat, G Mohan, J Lukose, S Shastry… - Transfusion Medicine …, 2024 - karger.com
Background: Raman tweezers spectroscopy (RTS) is a powerful tool that combines optical
tweezers and Raman spectroscopy to study single living cells. RTS has become …

Optical tweezers combined with micro‐Raman investigation of alcohol‐induced changes on single, live red blood cells in blood plasma

J Lukose, MN, G Mohan, S Shastry… - Journal of Raman …, 2019 - Wiley Online Library
Alcohol is commonly used as sterilizing agent in hospital settings. Alcohol abuse is also
associated with numerous medical complications. It influences the coagulation mechanics …

Laser Raman tweezer spectroscopy to explore the bisphenol A-induced changes in human erythrocytes

J Lukose, N Mithun, M Priyanka, G Mohan, S Shastry… - RSC …, 2019 - pubs.rsc.org
The dermal penetration of bisphenol-A (BPA) from thermal papers into the human skin is a
matter of major health concern due to its extensive use in developing countries like India …

Optical Tweezers in Raman Spectroscopy

B Ray, S Raj - Raman Spectroscopy: Advances and Applications, 2024 - Springer
Optical tweezers and Raman spectroscopy (OTRS) are two powerful techniques widely used
in the field of biophysics for studying the structural and mechanical properties of biological …