Regulation of cell signalling by uPAR
HW Smith, CJ Marshall - Nature reviews Molecular cell biology, 2010 - nature.com
Urokinase-type plasminogen activator receptor (uPAR) expression is elevated during
inflammation and tissue remodelling and in many human cancers, in which it frequently …
inflammation and tissue remodelling and in many human cancers, in which it frequently …
suPAR: the molecular crystal ball
M Thunø, B Macho, J Eugen-Olsen - Disease markers, 2009 - Wiley Online Library
soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and
elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in …
elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in …
The plasminogen activator inhibitor-1 paradox in cancer: a mechanistic understanding
MH Kubala, YA DeClerck - Cancer and Metastasis Reviews, 2019 - Springer
The paradoxical pro-tumorigenic function of plasminogen activator inhibitor 1 (PAI-1, aka
Serpin E1) in cancer progression and metastasis has been the subject of an abundant …
Serpin E1) in cancer progression and metastasis has been the subject of an abundant …
Modification of kidney barrier function by the urokinase receptor
C Wei, CC Möller, MM Altintas, J Li, K Schwarz… - Nature medicine, 2008 - nature.com
Podocyte dysfunction, represented by foot process effacement and proteinuria, is often the
starting point for progressive kidney disease. Therapies aimed at the cellular level of the …
starting point for progressive kidney disease. Therapies aimed at the cellular level of the …
Circulating soluble urokinase plasminogen activator receptor predicts cancer, cardiovascular disease, diabetes and mortality in the general population
J Eugen‐Olsen, O Andersen… - Journal of internal …, 2010 - Wiley Online Library
Eugen‐Olsen J, Andersen O, Linneberg A, Ladelund S, Hansen TW, Langkilde A, Petersen
J, Pielak T, Møller LN, Jeppesen J, Lyngbæk S, Fenger M, Olsen MH, Hildebrandt PR, Borch …
J, Pielak T, Møller LN, Jeppesen J, Lyngbæk S, Fenger M, Olsen MH, Hildebrandt PR, Borch …
[HTML][HTML] Pentoxifylline and berberine mitigate diclofenac-induced acute nephrotoxicity in male rats via modulation of inflammation and oxidative stress
Nephrotoxicity (NT) is a renal-specific situation caused by different toxins and drugs like non-
steroidal anti-inflammatory drugs (NSAIDs). NSAIDs like diclofenac (DCF) lead to glomerular …
steroidal anti-inflammatory drugs (NSAIDs). NSAIDs like diclofenac (DCF) lead to glomerular …
An insight into recent advances on platelet function in health and disease
PK Chaudhary, S Kim, S Kim - International journal of molecular sciences, 2022 - mdpi.com
Platelets play a variety of roles in vascular biology and are best recognized as primary
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …
Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in …
A Koch, S Voigt, C Kruschinski, E Sanson, H Dückers… - Critical care, 2011 - Springer
Introduction suPAR is the soluble form of the urokinase plasminogen activator receptor
(uPAR), which is expressed in various immunologically active cells. High suPAR serum …
(uPAR), which is expressed in various immunologically active cells. High suPAR serum …
[HTML][HTML] The urokinase receptor: focused cell surface proteolysis, cell adhesion and signaling
F Blasi, N Sidenius - FEBS letters, 2010 - Elsevier
Plasma membrane urokinase-type plasminogen activator (uPA)-receptor (uPAR) is a GPI-
anchored protein that binds with high-affinity and activates the serine protease uPA, thus …
anchored protein that binds with high-affinity and activates the serine protease uPA, thus …
Cardiovascular biomarkers: lessons of the past and prospects for the future
F Omran, I Kyrou, F Osman, VG Lim… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are a major healthcare burden on the population
worldwide. Early detection of this disease is important in prevention and treatment to …
worldwide. Early detection of this disease is important in prevention and treatment to …