High drug-loading nanomedicines: progress, current status, and prospects
S Shen, Y Wu, Y Liu, D Wu - International journal of nanomedicine, 2017 - Taylor & Francis
Drug molecules transformed into nanoparticles or endowed with nanostructures with or
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …
Designing smart polymer conjugates for controlled release of payloads
Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …
polymer materials that are responsive to change of environmental stimuli. Drugs can be …
Self-assembled nanostructures from amphiphilic block copolymers prepared via ring-opening metathesis polymerization (ROMP)
S Varlas, SB Lawrenson, LA Arkinstall… - Progress in Polymer …, 2020 - Elsevier
The development of controlled/living polymerization methodologies has underpinned a
rapid expanse in our understanding of amphiphilic block copolymer self-assembly. In …
rapid expanse in our understanding of amphiphilic block copolymer self-assembly. In …
Cylindrical polymer brushes–Anisotropic building blocks, unimolecular templates and particulate nanocarriers
M Müllner, AHE Müller - Polymer, 2016 - Elsevier
This article presents an overview of the latest key developments and research activities in
the area of cylindrical polymer brushes (CPBs), also known as 'molecular bottlebrushes' …
the area of cylindrical polymer brushes (CPBs), also known as 'molecular bottlebrushes' …
Polymer-drug conjugates: Design principles, emerging synthetic strategies and clinical overview
Adagen, an enzyme replacement treatment for adenosine deaminase deficiency, was the
first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval …
first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval …
Recent advances in formulation and application of molecular polymer brushes in biomedicine: Therapeutic, diagnostic, and theranostics capabilities
F Adeli, F Abbasi, P Ghandforoushan, HE Külahlı… - Nano Today, 2023 - Elsevier
The applications of nanotechnology in medical sciences, especially in drug and gene
delivery, has experienced unprecedented growth in recent years. The integration of …
delivery, has experienced unprecedented growth in recent years. The integration of …
Grubbs' and Schrock's catalysts, ring opening metathesis polymerization and molecular brushes—synthesis, characterization, properties and applications
I Choinopoulos - Polymers, 2019 - mdpi.com
In this review, molecular brushes and other macromolecular architectures bearing a
bottlebrush segment where the main chain is synthesized by ring opening metathesis …
bottlebrush segment where the main chain is synthesized by ring opening metathesis …
Molecular polymer brushes in nanomedicine
M Müllner - Macromolecular Chemistry and Physics, 2016 - Wiley Online Library
Nanomedicine is one of the fastest growing areas of nanotechnology. The control over
nanoparticle design and the ability to tailor nanoparticle performance to fit exacting …
nanoparticle design and the ability to tailor nanoparticle performance to fit exacting …
Engineering of molecular geometry in bottlebrush polymers
Bottlebrush polymers are large cylindrical macromolecules, where a molecular “width”
emerges from a large number of side chains densely attached to a central backbone. The …
emerges from a large number of side chains densely attached to a central backbone. The …
Near-infrared fluorescent micelles from poly (norbornene) brush triblock copolymers for nanotheranostics
This contribution describes the design and synthesis of multifunctional micelles based on
amphiphilic brush block copolymers (BBCPs) for imaging and selective drug delivery of …
amphiphilic brush block copolymers (BBCPs) for imaging and selective drug delivery of …