Sinonasal malignancies make up< 5% of all head and neck neoplasms, with an incidence of
0.5–1.0 per 100,000. The outcome of these rare malignancies has been poor, whereas …

It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …

Persistent infection by EBV is explained by the germinal center model (GCM) which provides
a satisfying and currently the only explanation for EBVs disparate biology. Since the GCM …

Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …

▪ Abstract The transcription factor NF-κB has attracted widespread attention among
researchers in many fields based on the following: its unusual and rapid regulation, the wide …

Since its discovery 50 years ago, Epstein-Barr virus (EBV) has been linked to the
development of cancers originating from both lymphoid and epithelial cells. Approximately …

Current knowledge is insufficient to explain why only a proportion of individuals exposed to
environmental carcinogens or carrying a genetic predisposition to cancer develop disease …

Epstein–Barr virus (EBV) was discovered 40 years ago from examining electron
micrographs of cells cultured from Burkitt's lymphoma, a childhood tumour that is common in …