Polyphenols targeting MAPK mediated oxidative stress and inflammation in rheumatoid arthritis

T Behl, T Upadhyay, S Singh, S Chigurupati… - Molecules, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder, predominantly
symmetric, which causes joint inflammation, cartilage degeneration and bone erosion …

Oxidative stress relevance in the pathogenesis of the rheumatoid arthritis: a systematic review

CM Quiñonez-Flores… - BioMed research …, 2016 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease whose pathogenic
mechanisms remain to be elucidated. The oxidative stress and antioxidants play an …

Increased reactive oxygen species formation and oxidative stress in rheumatoid arthritis

S Mateen, S Moin, AQ Khan, A Zafar, N Fatima - PloS one, 2016 - journals.plos.org
Background Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder. Highly
reactive oxygen free radicals are believed to be involved in the pathogenesis of the disease …

Redox status expressed as GSH: GSSG ratio as a marker for oxidative stress in paediatric tumour patients

O Zitka, S Skalickova, J Gumulec… - Oncology …, 2012 - spandidos-publications.com
Oxidative stress causes profound alterations of various biological structures, including
cellular membranes, lipids, proteins and nucleic acids, and it is involved in numerous …

Glutathione dysregulation and the etiology and progression of human diseases

N Ballatori, SM Krance, S Notenboom, S Shi, K Tieu… - 2009 - degruyter.com
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell
differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH …

Redox signalling and the inflammatory response in rheumatoid arthritis

LI Filippin, R Vercelino, NP Marroni… - Clinical & Experimental …, 2008 - academic.oup.com
Reactive oxygen species (ROS) are produced mainly during oxidative phosphorylation and
by activated phagocytic cells during oxidative burst. The excessive production of ROS can …

Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis

CC Tsai, HS Chen, SL Chen, YP Ho… - Journal of …, 2005 - Wiley Online Library
Objectives: Reactive oxygen species (ROS) are implicated in the destruction of the
periodontium during inflammatory periodontal diseases. The imbalance in …

Pharmacological aspects of natural quercetin in rheumatoid arthritis

M Tang, Y Zeng, W Peng, X Xie, Y Yang… - Drug Design …, 2023 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic autoimmune disease that can lead to severe joint
damage, disability and mortality. Quercetin (QUE) is a natural flavonoid that is ubiquitous in …

Compromised GCF total antioxidant capacity in periodontitis: cause or effect?

ILC Chapple, GR Brock, MR Milward… - Journal of clinical …, 2007 - Wiley Online Library
Background: Oxidative stress is implicated in the pathogenesis of periodontitis. The total
antioxidant capacity (TAOC) of gingival crevicular fluid volume (GCF) and plasma appears …

Curcumin and rheumatoid arthritis: A systematic review of literature

F Pourhabibi‐Zarandi… - … Journal of Clinical …, 2021 - Wiley Online Library
Background Curcumin is a natural polyphenol and the main compound from the rhizome of
Turmeric (Curcuma longa) and other Curcuma species. It has been widely used for different …