Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …

Drug repositioning is a strategy for identifying new antitumor drugs; this strategy allows
existing and approved clinical drugs to be innovatively repurposed to treat tumors. Based on …

Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a parasitic
infection that usually progresses to coma and death unless treated. WHO has updated its …

Background For a full treatment course of severe malaria, community-administered pre-
referral rectal artesunate (RAS) should be completed by post-referral treatment consisting of …

Background Under-five malaria in Nigeria is a leading cause of global child mortality,
accounting for 95,000 annual child deaths. High out-of-pocket medical expenditure …

At present, Artemisia annua L. is the major source of artemisinin production. To control the
outbreaks of malaria, artemisinin combination therapies (ACTs) are recommended, and …

Drug resistance and the severe side effects of chemotherapy necessitate the development of
novel anticancer drugs. Natural products are a valuable source for drug development …

Background Malaria is endemic in French Guiana (FG), South America. Despite the
decrease in cases in the local population, illegal gold miners are very affected by malaria …

Artemisinin represents a showcase example not only for the activity of medicinal herbs
deriving from traditional chinese medicine, but for phytotherapy in general. Its isolation from …

Background Recent reports of artemisinin partial resistance from Rwanda and Uganda are
worrisome and suggest a future policy change to adopt new anti-malarials. This is a case …