[HTML][HTML] Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome
SA Dabravolski, NG Nikiforov, AH Eid… - International journal of …, 2021 - mdpi.com
Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …
[HTML][HTML] Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …
disorder that manifests in genetically susceptible women following a range of negative …
[HTML][HTML] Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis
J Zou, Y Li, N Liao, J Liu, Q Zhang, M Luo… - Journal of ovarian …, 2022 - Springer
Background Accumulating evidence suggests a strong association between polycystic ovary
syndrome (PCOS) and ovarian cancer (OC), but the potential molecular mechanism remains …
syndrome (PCOS) and ovarian cancer (OC), but the potential molecular mechanism remains …
[HTML][HTML] Integrated multi-omics analysis reveals the molecular interplay between circadian clocks and cancer pathogenesis
A Pérez-Villa, G Echeverría-Garcés… - Scientific Reports, 2023 - nature.com
Circadian rhythms (CRs) are fundamental biological processes that significantly impact
human well-being. Disruption of these rhythms can trigger insufficient neurocognitive …
human well-being. Disruption of these rhythms can trigger insufficient neurocognitive …
[HTML][HTML] The epigenetic correlation among ovarian cancer, endometriosis and PCOS: A review
HT PK, L Unnikrishnan, M Pangath… - Critical reviews in …, 2022 - Elsevier
Ovarian cancer is a frequent malignancy that affects a large percentage of women.
Endometriosis is a chronic condition, where there is a production of benign lesions were …
Endometriosis is a chronic condition, where there is a production of benign lesions were …
[HTML][HTML] Pathophysiological effects of contemporary lifestyle on evolutionary-conserved survival mechanisms in polycystic ovary syndrome
J Parker - Life, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is increasingly being characterized as an evolutionary
mismatch disorder that presents with a complex mixture of metabolic and endocrine …
mismatch disorder that presents with a complex mixture of metabolic and endocrine …
Mitochondrial dysfunction in polycystic ovary syndrome
J Finsterer - Reproductive Sciences, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a multi-causal condition. Among the genetic causes,
variations in the mitochondrial DNA (mtDNA) are increasingly recognised as causative …
variations in the mitochondrial DNA (mtDNA) are increasingly recognised as causative …
[HTML][HTML] Unraveling druggable cancer-driving proteins and targeted drugs using artificial intelligence and multi-omics analyses
A López-Cortés, A Cabrera-Andrade… - Scientific Reports, 2024 - nature.com
The druggable proteome refers to proteins that can bind to small molecules with appropriate
chemical affinity, inducing a favorable clinical response. Predicting druggable proteins …
chemical affinity, inducing a favorable clinical response. Predicting druggable proteins …
The pharmacoepigenetic paradigm in cancer treatment
B Ocaña-Paredes, S Rivera-Orellana… - Frontiers in …, 2024 - frontiersin.org
Epigenetic modifications, characterized by changes in gene expression without altering the
DNA sequence, play a crucial role in the development and progression of cancer by …
DNA sequence, play a crucial role in the development and progression of cancer by …
[HTML][HTML] Tracing the pathways and mechanisms involved in medicinal uses of flaxseed with computational methods and bioinformatics tools
S Joshi, R Srivastava - Frontiers in Chemistry, 2024 - frontiersin.org
Pharmacological drugs targeting specific pathways involved in various diseases have seen
recent advancement with newer and more efficient emerging drug targets, but these drugs …
recent advancement with newer and more efficient emerging drug targets, but these drugs …