Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Microfluidic point-of-care (POC) devices in early diagnosis: A review of opportunities and challenges

SM Yang, S Lv, W Zhang, Y Cui - Sensors, 2022 - mdpi.com
The early diagnosis of infectious diseases is critical because it can greatly increase recovery
rates and prevent the spread of diseases such as COVID-19; however, in many areas with …

Biomedical applications of microfluidic devices: a review

G Gharib, İ Bütün, Z Muganlı, G Kozalak, İ Namlı… - Biosensors, 2022 - mdpi.com
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …

Large-area interfaces for single-molecule label-free bioelectronic detection

E Macchia, F Torricelli, P Bollella, L Sarcina… - Chemical …, 2022 - ACS Publications
Bioelectronic transducing surfaces that are nanometric in size have been the main route to
detect single molecules. Though enabling the study of rarer events, such methodologies are …

[HTML][HTML] Emerging multianalyte biosensors for the simultaneous detection of protein and nucleic acid biomarkers

A Klebes, HC Ates, RD Verboket, GA Urban… - Biosensors and …, 2024 - Elsevier
Traditionally, biosensors are designed to detect one specific analyte. Nevertheless, disease
progression is regulated in a highly interactive way by different classes of biomolecules like …

Recent developments of point-of-care (POC) testing platform for biomolecules

Y Manmana, T Kubo, K Otsuka - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Abstract Point-of-care (POC) testing devices are necessary to improve human life with many
aspects both for developing and developed countries. Especially, the specific biomolecules …

Electrochemical vs. optical biosensors for point-of-care applications: A critical Review

SRS Pour, D Calabria, A Emamiamin, E Lazzarini… - Chemosensors, 2023 - mdpi.com
Analytical chemistry applied to medical and diagnostic analysis has recently focused on the
development of cost-effective biosensors able to monitor the health status or to assess the …

Microfluidics in cardiovascular disease research: state of the art and future outlook

Q Ma, H Ma, F Xu, X Wang, W Sun - Microsystems & Nanoengineering, 2021 - nature.com
Due to extremely severe morbidity and mortality worldwide, it is worth achieving a more in-
depth and comprehensive understanding of cardiovascular diseases. Tremendous effort has …

Advances in multiplex electrical and optical detection of biomarkers using microfluidic devices

KR Mitchell, JE Esene, AT Woolley - Analytical and Bioanalytical …, 2022 - Springer
Microfluidic devices can provide a versatile, cost-effective platform for disease diagnostics
and risk assessment by quantifying biomarkers. In particular, simultaneous testing of several …

Microfluidics for diagnosis and treatment of cardiovascular disease

Y Ma, C Liu, S Cao, T Chen, G Chen - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
Cardiovascular disease (CVD), a type of circulatory system disease related to the lesions of
the cardiovascular system, has become one of the main diseases that endanger human …