The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …

The realization that low–glycemic index diets were formulated using resistant starch led to
more than a decade of research on the health effects of resistant starch. Determination of the …

Although epidemiologic studies carried out in Taiwan, Bangladesh, and Sweden have
demonstrated a diabetogenic effect of arsenic, the mechanisms remain unclear and require …

Adrenomedullin (ADM) is a 52-amino acid peptide with structural homology to calcitonin
gene-related peptide (CGRP) initially isolated from human pheochromocytoma. ADM is …

Adrenomedullin (AM) is a peptide involved both in the pathogenesis of cardiovascular
diseases and in circulatory homeostasis. The high-affinity AM receptor is composed of …

Aims/hypothesis Oxidative stress is associated with diabetes, hypertension and
atherosclerosis. Insulin resistance is implicated in the development of these disorders. We …

Fat cells or adipocytes are distributed ubiquitously throughout the body and are often
regarded purely as energy stores. However, recently it has become clear that these …

The bioactive peptide adrenomedullin (AM) exerts pleiotropic actions in various organs and
tissues. In the heart, AM has an inhibitory effect on ventricular remodeling, suppressing …

Objective—The acquisition of arterial or venous identity is highlighted in vascular
development. Previously, we have reported an embryonic stem (ES) cell differentiation …

Background—Revealing the mechanisms underlying the functional integrity of the vascular
system could make available novel therapeutic approaches. We previously showed that …