Background: Traumatic brain injury (TBI) is a leading cause of death and disability
worldwide. The use of machine learning (ML) has emerged as a key advancement in TBI …

Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact
remote to the optic nerve. The mechanism of injury is not understood, and there are no …

Traumatic brain injury (TBI) is the leading cause of death and permanent impairment over
the last decades. In both the severe and mild TBIs, diffuse axonal injury (DAI) is the most …

Disorders affecting the central nervous system are a leading cause of disability in the world.
Regenerative medicine using biomaterial-based therapies is a growing field that has …

Skin tissues are anisotropic, and their mechanical characteristics vary widely depending on
where they are located on the body. While some research has been conducted in the past to …

Human skin exhibits highly varying mechanical properties, thickness, hardness, and
anisotropy by virtue of changing fiber distributions and orientations, across different body …

Advanced neuroimaging provides new opportunities to enhance head injury models,
including the incorporation of white matter (WM) structural anisotropy. Information from high …

Given the complex nature of traumatic brain injury (TBI), assessment of injury risk directly
from kinematic measures of head motion remains a challenge. Despite this challenge …

Soft tissues in general exhibit anisotropic mechanical behavior, which varies in three
dimensions based on the location of the tissue in the body. In the past, there have been few …

Microscale brain injury studies suggest axonal elongation as a potential mechanism for
diffuse axonal injury (DAI). Recent studies have begun to incorporate white matter (WM) …