Pesticide regulations and their malpractice implications on food and environment safety
VL Zikankuba, G Mwanyika, JE Ntwenya… - Cogent Food & …, 2019 - Taylor & Francis
Although pesticides have a positive effect on plant health in terms of insect pests and
diseases control, increased productivity and improved crop storage, their malpractice …
diseases control, increased productivity and improved crop storage, their malpractice …
1, 3, 5‐Triazine: A versatile pharmacophore with diverse biological activities
S Singh, MK Mandal, A Masih, A Saha… - Archiv der …, 2021 - Wiley Online Library
Triazine and its derivatives have been the epicenter of chemotherapeutic molecules due to
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …
A comprehensive overview of β-carbolines and its derivatives as anticancer agents
B Luo, X Song - European Journal of Medicinal Chemistry, 2021 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …
diversity and outstanding antitumor activities. This review summarizes research …
Recent advancements in anti-leishmanial research: Synthetic strategies and structural activity relationships
Leishmaniasis is a parasitic neglected tropical disease caused by various species of
Leishmania parasite. Despite tremendous advancements in the therapeutic sector and drug …
Leishmania parasite. Despite tremendous advancements in the therapeutic sector and drug …
Synthesis, biological evaluation, structure–activity relationship, and mechanism of action studies of quinoline–metronidazole derivatives against experimental visceral …
A Upadhyay, P Chandrakar, S Gupta… - Journal of Medicinal …, 2019 - ACS Publications
In our efforts to identify novel chemical scaffolds for the development of antileishmanial
agents, a series of quinoline–metronidazole hybrid compounds was synthesized and tested …
agents, a series of quinoline–metronidazole hybrid compounds was synthesized and tested …
Design, synthesis, anti-cancer evaluation and binding mode studies of benzimidazole/benzoxazole linked β-carboline derivatives
R Sireesha, R Sreenivasulu, C Chandrasekhar… - Journal of Molecular …, 2021 - Elsevier
A new series of benzimidazole/benzoxazole linked β-carbolines (9a-j) were rationally
designed and synthesized by combining two different anti-cancer fragments. The new hybrid …
designed and synthesized by combining two different anti-cancer fragments. The new hybrid …
Recent biological applications of heterocyclic hybrids containing s-triazine scaffold
s-Triazine possesses an auspicious status in the field of drug discovery and development
owing to its presence in many naturally occurring compounds as well as commercially …
owing to its presence in many naturally occurring compounds as well as commercially …
Recent developments on synthesis strategies, SAR studies and biological activities of β-carboline derivatives–an update
The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …
of these alkaloids and their derivatives have been found to show significant biological …
Chromatography-Free Synthesis of β-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of β-Carbolines as …
Agrochemical science prioritizes the discovery and effective synthesis of innovative and
promising lead compounds. Herein, we developed an efficient column chromatography-free …
promising lead compounds. Herein, we developed an efficient column chromatography-free …
Insights into the current status of privileged N-heterocycles as antileishmanial agents
Leishmania, one of the most important neglected tropical diseases, is endemic in several
regions of the world and hence regarded as a serious threat to public health. Major …
regions of the world and hence regarded as a serious threat to public health. Major …