Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …

Due to the negative impact of reactive species (including free radicals) on humans and
animals, the investigations to find effective substances (antioxidants), which protect living …

Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a
risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various …

Abstract Non‐alcoholic steatohepatitis (NASH), the progressive form of non‐alcoholic fatty
liver disease (NAFLD), is emerging as a main health problem in industrialized countries …

Insulin resistance, oxidative stress, hyperlipidemia, and inflammation play main roles in the
development of nonalcoholic fatty liver disease (NAFLD). Some studies have reported that …

The fruits of citrus family are rich in flavonoids with superior antioxidant properties; citrus
bioactive components are potentially beneficial without adverse effects or cytotoxicity in …

Mitochondria are the respiratory and energetic centers of the cell where multiple intra-and
extracellular signal transduction pathways converge leading to dysfunction of those …

This study aimed to investigate effects of citrus flavanones naringenin (NAR) and hesperetin
(HES) on liver antioxidant status and membrane phospholipid composition in 24-month-old …

Background Currently, there is no approved medication for non-alcoholic fatty liver disease
management. Pre-clinical and clinical studies showed that several bioactive molecules in …

A number of studies have confirmed anti-tumor activity of flavonoids and their ability to
enhance the effectiveness of classical anticancer drugs. The mechanism of this …