Hemodynamic regulation allows stable growth of microvascular networks

Y Qi, SS Chang, Y Wang, C Chen… - Proceedings of the …, 2024 - National Acad Sciences
How do vessels find optimal radii? Capillaries are known to adapt their radii to maintain the
shear stress of blood flow at the vessel wall at a set point, yet models of adaptation purely …

Lymphatic uptake of biotherapeutics through a 3D hybrid discrete-continuum vessel network in the skin tissue

D Han, C Li, S Araimdeh, V Sree, E Rahimi… - Journal of Controlled …, 2023 - Elsevier
Subcutaneous administration is a common approach for the delivery of biotherapeutics,
which is achieved mainly through the absorption across lymphatic vessels. In this paper, the …

High-throughput imaging of blood flow reveals developmental changes in distribution patterns of hemodynamic quantities in developing zebrafish

SS Maung Ye, JK Kim, NT Carretero… - Frontiers in Physiology, 2022 - frontiersin.org
Mechanical forces from blood flow and pressure (hemodynamic forces) contribute to the
formation and shaping of the blood vascular network during embryonic development …

Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy

Z Wang, R Zhao, DA Wagenaar, D Espino, L Sheintuch… - bioRxiv, 2024 - biorxiv.org
Volumetric functional imaging of transient cellular signaling and motion dynamics poses a
significant challenge to current microscopy techniques, primarily due to limitations in …

Fluid-Structure Interaction Modeling of the Aortic Hemodynamics in Adult Zebrafish: A Pilot Study Based on Synchrotron X-Ray Tomography

M Van Impe, L Caboor, V Deleeuw… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
Objective: The zebrafish is increasingly used as a small animal model for cardiovascular
disease, including vascular disorders. Nevertheless, a comprehensive biomechanical …

A cell-and-plasma numerical model reveals hemodynamic stress and flow adaptation in zebrafish microvessels after morphological alteration

SS Maung Ye, LK Phng - PLOS Computational Biology, 2023 - journals.plos.org
The development of a functional cardiovascular system ensures a sustainable oxygen,
nutrient and hormone delivery system for successful embryonic development and …

Combined computational analysis and cytology show limited depth osteogenic effect on bone defects in negative pressure wound therapy

XH Huang, LQ Zheng, YX Dai, SN Hu… - … in Bioengineering and …, 2023 - frontiersin.org
Background: The treatment of bone defects remains a clinical challenge. The effect of
negative pressure wound therapy (NPWT) on osteogenesis in bone defects has been …

An Image-Based Framework for the Analysis of the Murine Microvasculature: From Tissue Clarification to Computational Hemodynamics

S Mañosas, A Sanz, C Ederra, A Urbiola… - Mathematics, 2022 - mdpi.com
The blood–brain barrier is a unique physiological structure acting as a filter for every
molecule reaching the brain through the blood. For this reason, an effective pharmacologic …

High-speed Volumetric Functional Imaging with Light Field Microscopy

Z Wang - 2024 - search.proquest.com
The continuous advancement in microscopy has been unveiling the hidden world of tissues,
cells, and molecules. In the quest for deeper spatiotemporal insights into biological …

[图书][B] Microvascular Hydrodynamics: Structure and Adaptation Principles

Y Qi - 2022 - search.proquest.com
Microvasculature structures vary drastically from species to species, and from organs to
organs. Different structures signify inclinations of distinct blood flow perfusion features …