Nanoprobes for PET/MR imaging

H Liu, R Wang, H Gao, L Chen, X Li, X Yu… - Advanced …, 2024 - Wiley Online Library
The development of clinical imaging techniques significantly improves diagnostic accuracy
and provides guidance for personalized treatment of individuals. However, every single …

Nanoparticle-based therapeutic strategies for enhanced pancreatic ductal adenocarcinoma immunotherapy

W Hou, B Yang, H Zhu - Pharmaceutics, 2022 - mdpi.com
Immunotherapy has dramatically changed prognosis for patients with malignant tumors.
However, as a non-immunogenic tumor, pancreatic ductal adenocarcinoma (PDAC) has a …

177Lu-Labeled Iron Oxide Nanoparticles Functionalized with Doxorubicin and Bevacizumab as Nanobrachytherapy Agents against Breast Cancer

EA Salvanou, A Kolokithas-Ntoukas, D Prokopiou… - Molecules, 2024 - mdpi.com
The use of conventional methods for the treatment of cancer, such as chemotherapy or
radiotherapy, and approaches such as brachytherapy in conjunction with the unique …

Methods for Radiolabeling Nanoparticles (Part 3): Therapeutic Use

V Bentivoglio, P Nayak, M Varani, C Lauri, A Signore - Biomolecules, 2023 - mdpi.com
Following previously published systematic reviews on the diagnostic use of nanoparticles
(NPs), in this manuscript, we report published methods for radiolabeling nanoparticles with …

Synthesis and Preclinical Evaluation of a Bispecific PSMA-617/RM2 Heterodimer Targeting Prostate Cancer

C Liolios, D Bouziotis, W Sihver… - ACS Medicinal …, 2024 - ACS Publications
Prostate-specific membrane antigen (PSMA) and gastrin-releasing peptide receptor (GRPR)
have been used for diagnostic molecular imaging/therapy of prostate cancer (PCa). To …

Recent Advances in Metal Oxide and Phosphate Nanomaterials Radiolabeling with Medicinal Nuclides

T Janská, M Sakmár, M Štíbr, M Vlk, J Kozempel - ACS omega, 2024 - ACS Publications
The utilization of nanomaterials in biomedical applications has surged in recent years; yet,
the transition from research to practical implementation remains a great challenge. However …

Radiation nanomedicines for cancer treatment: a scientific journey and view of the landscape

RM Reilly, CJ Georgiou, MK Brown, Z Cai - EJNMMI Radiopharmacy and …, 2024 - Springer
Background Radiation nanomedicines are nanoparticles labeled with radionuclides that
emit α-or β-particles or Auger electrons for cancer treatment. We describe here our 15 years …

Unveiling Nanoparticles: Recent Approaches in Studying the Internalization Pattern of Iron Oxide Nanoparticles in Mono-and Multicellular Biological Structures

TE Petcov, M Straticiuc, D Iancu, DA Mirea… - Journal of Functional …, 2024 - mdpi.com
Nanoparticle (NP)-based solutions for oncotherapy promise an improved efficiency of the
anticancer response, as well as higher comfort for the patient. The current advancements in …

In Vitro Assessment of 177Lu-Labeled Trastuzumab-Targeted Mesoporous Carbon@Silica Nanostructure for the Treatment of HER2-Positive Breast Cancer

A Tunçel, S Maschauer, O Prante, F Yurt - Pharmaceuticals, 2024 - mdpi.com
This study assessed the effectiveness of a trastuzumab-targeted 177Lu-labeled mesoporous
Carbon@ Silica nanostructure (DOTA@ TRA/MC@ Si) for HER2-positive breast cancer …

Black TiO2-based nanoparticles as Toll-like receptor stimulator delivery system for enhanced photothermal-immunotherapy of pancreatic cancer

L Xu, R Wu, J Ni, L Jin, K Xu, Y Zhu, L Hong… - Cancer …, 2024 - Springer
Background The tumor-specific immune responses, essential for removing residual lesions
and preventing tumor metastases, can be stimulated by tumor-associated antigens (TAAs) …