Wnt5a is the prototypical activator of the non-canonical Wnt pathways, and its
overexpression has been implicated in the progression of several tumor types by promoting …

The wingless-related integration site (Wnt) signaling pathway plays an essential role in
embryonic development and nervous system regulation. It is critically involved in multiple …

Chronic pain is a debilitating condition that influences the social, economic, and
psychological aspects of patients' lives. Hence, the need for better treatment is drawing …

It is well-established that aberrant WNT expression and signaling is associated with
developmental defects, malignant transformation and carcinogenesis. More recently, WNT …

Chronic pain is a prevalent neurological complication among individuals living with human
immunodeficiency virus (PLHIV) in the post-combination antiretroviral therapy (cART) era …

Wnt signalling is an essential pathway in embryogenesis, differentiation, cell motility,
development, and adult tissue homeostasis in vertebrates. The Wnt signalling network can …

In the management of human immunodeficiency virus (HIV) infection around the world,
chronic complications are becoming a new problem along with the prolonged life …

Wnt5a has been found recently to be involved in inflammation regulation through a
mechanism that remains unclear. Immunohistochemical staining of infected human dental …

Brain-derived neurotrophic factor (BDNF) is a master regulator of synaptic plasticity in
various neural circuits of the mammalian central nervous system. Neuron activity–induced …

Reactive astrocytes are commonly activated in the spinal dorsal horn (SDH) of various
animal models of pathological pain. Previous investigations suggest an association between …