The impact of regional versus general anesthesia on postoperative neurocognitive outcomes in elderly patients undergoing hip fracture surgery: A systematic review …

S Bhushan, X Huang, Y Duan, Z Xiao - International journal of surgery, 2022 - Elsevier
Background Randomized trials have shown conflicting results regarding differences in
outcomes according to anesthesia type on the prevalence of postoperative delirium (POD) …

Perioperative factors associated with postoperative delirium in patients undergoing noncardiac surgery: An individual patient data meta-analysis

B Sadeghirad, BT Dodsworth, NS Gelsomino… - JAMA network …, 2023 - jamanetwork.com
Importance Postoperative delirium (POD) is a common and serious complication after
surgery. Various predisposing factors are associated with POD, but their magnitude and …

Association between intraoperative arterial hypotension and postoperative delirium after noncardiac surgery: a retrospective multicenter cohort study

LJ Wachtendorf, O Azimaraghi, P Santer… - Anesthesia & …, 2022 - journals.lww.com
BACKGROUND: It is unclear whether intraoperative arterial hypotension is associated with
postoperative delirium. We hypothesized that intraoperative hypotension within a range …

A randomized, controlled clinical trial comparing remimazolam to propofol when combined with alfentanil for sedation during ERCP procedures

SA Dong, Y Guo, SS Liu, LL Wu, LN Wu, K Song… - Journal of clinical …, 2023 - Elsevier
Study objective In many countries, the combination of propofol and opioid is used as the
preferred sedative regime during ERCP. However, the most serious risks of propofol …

Perioperative neurocognitive disorders: a narrative review focusing on diagnosis, prevention, and treatment

H Kong, LM Xu, DX Wang - CNS Neuroscience & therapeutics, 2022 - Wiley Online Library
Perioperative neurocognitive disorders (NCDs) refer to neurocognitive abnormalities
detected during the perioperative periods, including preexisting cognitive impairment …

Association of postoperative delirium with cognitive outcomes: a meta-analysis

H Huang, H Li, X Zhang, G Shi, M Xu, X Ru… - Journal of Clinical …, 2021 - Elsevier
Study objective To determine the association between postoperative delirium (POD) and
cognitive outcomes at least 1 month after surgery in elderly patients, and synthesize the …

Effect of remimazolam on postoperative delirium in older adult patients undergoing orthopedic surgery: a prospective randomized controlled clinical trial

JJ Yang, L Lei, D Qiu, S Chen, LK Xing… - Drug Design …, 2023 - Taylor & Francis
Background Postoperative delirium is common in older adult patients and associated with a
poor prognosis. The use of benzodiazepine was identified as an independent risk factor for …

[HTML][HTML] Could dexmedetomidine be repurposed as a glymphatic enhancer?

NDÅ Persson, P Uusalo, M Nedergaard… - Trends in …, 2022 - cell.com
Cerebrospinal fluid (CSF) flows through the central nervous system (CNS) via the
glymphatic pathway to clear the interstitium of metabolic waste. In preclinical studies …

[HTML][HTML] Influence of perioperative dexmedetomidine on the incidence of postoperative delirium in adult patients undergoing cardiac surgery

M Patel, DN Onwochei, N Desai - British Journal of Anaesthesia, 2022 - Elsevier
Background Delirium is a common neurocognitive complication after cardiac surgery. The
aim of this systematic review was to determine whether the administration of …

[HTML][HTML] Postoperative delirium in geriatric patients with hip fractures

Y Chen, S Liang, H Wu, S Deng, F Wang… - Frontiers in aging …, 2022 - frontiersin.org
Postoperative delirium (POD) is a frequent complication in geriatric patients with hip
fractures, which is linked to poorer functional recovery, longer hospital stays, and higher …