Infective endocarditis is a life‐threatening and enigmatic disease with a mortality of 30% and
a pathophysiology that is poorly understood. However, at its core, an endocarditis lesion is …

Infective endocarditis is a relatively rare, but deadly cause of sepsis, with an overall mortality
ranging from 20 to 25% in most series. Although the classic clinical classification into …

Over the past 10 years, neutrophil extracellular traps (NETs) have become widely accepted
as an integral player in immunothrombosis, due to their complex interplay with both …

Infective endocarditis (IE) is a life-threatening infective disease with increasing incidence
worldwide. From early on, in the antibiotic era, it was recognized that high-dose and long …

Background: Infective endocarditis (IE) is characterized by an infected thrombus at the heart
valves. How bacteria bypass the immune system and cause these thrombi remains unclear …

Over the last decade, the incidence of infective endocarditis (IE) has increased, with a
change in the frequency of causative bacteria. Early evidence has substantially …

Importance The use of warfarin to prevent thromboembolism in patients with infective
endocarditis (IE) remains controversial due to potentially increased bleeding risks. Design …

Infective endocarditis is a life-threatening infection of heart valves and adjacent structures
characterized by vegetations on valves and other endocardial surfaces, with tissue …

Patients with infective endocarditis (IE) form a heterogeneous group by age, co-morbidities
and severity ranging from stable patients to patients with life-threatening complications with …

Infective endocarditis (IE) is a heart valve infection with high mortality rates. IE results from
epithelial lesions, inducing sterile healing vegetations consisting of platelets, leucocytes …