Modern risk stratification of acute myeloid leukemia in 2023: integrating established and emerging prognostic factors

E Boscaro, I Urbino, FM Catania, G Arrigo, C Secreto… - Cancers, 2023 - mdpi.com
Simple Summary Several factors, both patient-and disease-related, are essential to
accurately estimate acute myeloid leukemia (AML) prognosis. The rapidly evolving field …

The molecular context of oxidant stress response in cancer establishes ALDH1A1 as a critical target: What this means for acute myeloid leukemia

GM Dancik, L Varisli, SA Vlahopoulos - International Journal of Molecular …, 2023 - mdpi.com
The protein family of aldehyde dehydrogenases (ALDH) encompasses nineteen members.
The ALDH1 subfamily consists of enzymes with similar activity, having the capacity to …

Symptomatic Patients with Hyperleukocytic FLT3-ITD Mutated Acute Myeloid Leukemia Might Benefit from Leukapheresis

KMN Farid, T Sauer, M Schmitt, C Müller-Tidow… - Cancers, 2023 - mdpi.com
Simple Summary Leukostasis in hyperleukocytotic acute myeloid leukemia (AML) is a
medical emergency. The optimal treatment strategy and the potential benefits of …

Hyperleukocytosis in patients with acute myeloid leukemia admitted to the intensive care unit: a single-center retrospective analysis

JM Heger, B Böll, JH Naendrup, F Simon, CM Gräf… - Leukemia Research, 2023 - Elsevier
A relevant proportion of patients with acute myeloid leukemia (AML) presenting with
hyperleukocytosis are admitted to the intensive care unit (ICU). However, data on …

Characteristics and outcomes of patients with acute myeloid leukemia admitted to intensive care unit with acute respiratory failure: a post-hoc analysis of a prospective …

C Secreto, D Chean, A Van de Louw, A Kouatchet… - Annals of Intensive …, 2023 - Springer
Background Acute respiratory failure (ARF) is the leading cause of intensive care unit (ICU)
admission in patients with Acute Myeloid Leukemia (AML) and data on prognostic factors …

Management of hematological patients requiring emergency chemotherapy in the intensive care unit

A Lafarge, D Chean, L Whiting, R Clere-Jehl - Intensive care medicine, 2024 - Springer
Hematological malignancies may require rapid-onset treatment because of their short
doubling time, notably observed in acute leukemias and specific high-grade lymphomas …

高白细胞急性白血病常见近期并发症

何文娟, 陈智超, 胡豫 - 临床血液学杂志, 2024 - lcxy.whuhzzs.com
高白细胞急性白血病为血液科危重症, 早期死亡风险高, 其具有独特的临床表现,
流行病学特征及病理生理学机制. 白细胞淤滞, 肿瘤溶解综合征和弥散性血管内凝血是其常见的 …

Study on Leukapheresis of Hyperleukocyte Acute Myeloid Leukemia

R Pan, A Xu, L Liu, J Wu, X Li, G Chen, R Li, W Yin… - 2024 - researchsquare.com
Respiratory failure, intracranial hemorrhage and infection were more common in
hyperleukocyte acute myeloid leukemia patients than in non-hyperleukocyte leukemia …

Common short-term complications of hyperleukocytic acute leukemia

HE Wenjuan, C Zhichao, HU Yu - J Clin Hematol, 2024 - lcxyen.whuhzzs.com
Hyperleukocytic acute leukemia is a critical disease in the department of hematology with a
high risk of early death. It has unique clinical manifestations, epidemiological characteristics …