Circulating tumor cells are tumor cells with high vitality and high metastatic potential that
invade and shed into the peripheral blood from primary solid tumors or metastatic foci. Due …

The development of lab-on-a-chip (LOC) devices over the past decade has attracted
growing interest. LOC devices aim to achieve the miniaturization, integration, automation …

The ability to separate living cells is an essential aspect of cell research. Magnetic cell
separation methods are among some of the most efficient methods for bulk cell separation …

Metastasis is the main cause of tumor-related death, and the dispersal of tumor cells through
the circulatory system is a critical step in the metastatic process. Early detection and analysis …

Dielectrophoretic (DEP) force is exerted when a neutral particle is polarized in a non-uniform
electric field, and depends on the dielectric properties of the particle and the suspending …

A goal of modern biology is to understand the molecular mechanisms underlying cellular
function. The ability to manipulate and analyze single cells is crucial for this task. The advent …

DEP is an established technique for particle manipulation. Although first demonstrated in the
1950s, it was not until the development of miniaturization techniques in the 1990s that DEP …

The measurement and characterization of circulating tumor cells (CTCs) hold promise for
advancing personalized therapeutics. CTCs are the precursor to metastatic cancer and thus …

Abstract Circulating Tumor Cells (CTCs) represent a “liquid biopsy of the tumor” which might
allow real-time monitoring of cancer biology and therapies in individual patients. CTCs are …

Background: Molecular characterisation of single circulating tumour cells (CTCs) holds
considerable promise for predictive biomarker assessment and to explore CTC …