[HTML][HTML] Multiorgan-on-a-chip: a systemic approach to model and decipher inter-organ communication
N Picollet-D'hahan, A Zuchowska, I Lemeunier… - Trends in …, 2021 - cell.com
Multiorgan-on-a-chip (multi-OoC) platforms have great potential to redefine the way in which
human health research is conducted. After briefly reviewing the need for comprehensive …
human health research is conducted. After briefly reviewing the need for comprehensive …
High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
[HTML][HTML] Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development
U Marx, T Akabane, TB Andersson, E Baker… - Altex, 2020 - ncbi.nlm.nih.gov
The first microfluidic microphysiological systems (MPS) entered the academic scene more
than 15 years ago and were considered an enabling technology to human in vitro (patho) …
than 15 years ago and were considered an enabling technology to human in vitro (patho) …
[HTML][HTML] A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
I Maschmeyer, AK Lorenz, K Schimek, T Hasenberg… - Lab on a Chip, 2015 - pubs.rsc.org
Systemic absorption and metabolism of drugs in the small intestine, metabolism by the liver
as well as excretion by the kidney are key determinants of efficacy and safety for therapeutic …
as well as excretion by the kidney are key determinants of efficacy and safety for therapeutic …
Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease
Recent advances in biomaterials, microfabrication, microfluidics, and cell biology have led to
the development of organ-on-a-chip devices that can reproduce key functions of various …
the development of organ-on-a-chip devices that can reproduce key functions of various …
Liver organ-on-chip models for toxicity studies and risk assessment
T Messelmani, L Morisseau, Y Sakai, C Legallais… - Lab on a Chip, 2022 - pubs.rsc.org
The liver is a key organ that plays a pivotal role in metabolism and ensures a variety of
functions in the body, including homeostasis, synthesis of essential components, nutrient …
functions in the body, including homeostasis, synthesis of essential components, nutrient …
Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies
S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
[HTML][HTML] Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing
U Marx, TB Andersson, A Bahinski, M Beilmann… - Altex, 2016 - ncbi.nlm.nih.gov
The recent advent of microphysiological systems–microfluidic biomimetic devices that aspire
to emulate the biology of human tissues, organs and circulation in vitro–is envisaged to …
to emulate the biology of human tissues, organs and circulation in vitro–is envisaged to …
Recent advances in body-on-a-chip systems
Microphysiological systems (MPS, also known as “organ-on-a-chip”,“body-on-a-chip”, or
“human-on-a-chip”) have emerged over the last 15 years as attractive systems to probe …
“human-on-a-chip”) have emerged over the last 15 years as attractive systems to probe …