Melatonin is remarkably functionally diverse with actions as a free radical scavenger and
antioxidant, circadian rhythm regulator, anti‐inflammatory and immunoregulating molecule …

Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …

Oxidative stress has been proven to be related to the onset of a large number of health
disorders. This chemical stress is triggered by an excess of free radicals, which are …

The discovery of melatonin and its derivatives as antioxidants has stimulated a very large
number of studies which have, virtually uniformly, documented the ability of these molecules …

Melatonin has been shown to be an effective antioxidant in a number of experimental
models both in vitro and in vivo. Considering the data available, it is now clear that the …

Melatonin is a potent endogenous free radical scavenger, actions that are independent of its
many receptor-mediated effects. In the last several years, hundreds of publications have …

Melatonin exhibits extraordinary diversity in terms of its functions and distribution. When
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …

The reactions of melatonin (MLT) with hydroxyl and several peroxyl radicals have been
studied using the Density Functional Theory, specifically the M05-2X functional. Five …

Once thought to be exclusively a molecule of the animal kingdom, melatonin has now been
found to exist in plants as well. Among a number of actions, melatonin is a direct free radical …

We hypothesized that doxorubicin (DOX) induces cardiotoxicity of myocardium via oxygen
radicals. The present study is aimed at examining the membrane alterations by oxygen …