Hybrid azine derivatives: a useful approach for antimicrobial therapy

D Amariucai-Mantu, V Mangalagiu, I Bejan, A Aricu… - Pharmaceutics, 2022 - mdpi.com
Nowadays, infectious diseases caused by microorganisms are a major threat to human
health, mostly because of drug resistance, multi-drug resistance and extensive-drug …

Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic …

S Murugavel, C Ravikumar, G Jaabil… - … Biology and Chemistry, 2019 - Elsevier
Computational quantum chemical study and biological evaluation of a synthesized novel
sulfur heterocyclic thiophene derivative containing 1, 2, 3-triazole and pyridine moieties …

Catalytic application Fe3O4@ SiO2@(CH2) 3-urea-dithiocarbamic acid for the synthesis of triazole-linked pyridone derivatives

MR Anizadeh, M Torabi, MA Zolfigol, M Yarie - Journal of Molecular …, 2023 - Elsevier
In this study, synthesis and characterization of an acidic-hydrogen bonding dual role and
recoverable catalyst [Fe 3 O 4@ SiO 2@(CH 2) 3-urea-dithiocarbamic acid] was reported …

Pharmacological Perspectives of 2‐alkoxy‐3‐Cyanopyridine Scaffolds: An Up‐to‐Date Review

P Mahesha, NS Shetty - ChemistrySelect, 2024 - Wiley Online Library
Abstract The 2‐alkoxy‐3‐cyanopyridine derivatives' straightforward synthesis, ease of
structural manipulation, and variety of intriguing biological activity continue to captivate …

A New and an Eco‐Friendly Approach for the Construction of Multi‐Functionalized Benzenes with Computational Studies

T Damera, R Pagadala - Chemistry & Biodiversity, 2023 - Wiley Online Library
The new path chosen is more appropriate in the context of green chemistry. This research
aims to construct 5, 6, 7, 8‐tetrahydronaphthalene‐1, 3‐dicarbonitrile (THNDC) and 1, 2, 3, 4 …

Synthesis and exploration of anticancer potential of spirocyclic 1, 2, 3-triazoline and aziridine derivatives of natural eudesmanolide isoalantolactone

SS Patrushev, DO Kichkina, AD Moralev… - Bioorganic …, 2025 - Elsevier
Eudesmane-type sesquiterpene lactone isoalantolactone 1 is of great interest due to its
availability, biological activity and synthetic application. Respective series of original …

Synthesis and evaluation of antibacterial activity of bis-eudesmanolides connected by nitrogen-containing linkers

SS Patrushev, DO Vasil'eva, LG Burova… - Russian Chemical …, 2023 - Springer
The reaction of isoalantolactone with primary amines or piperazine proceeds under mild
conditions with high stereoselectivity to give 11, 13-isoalantolactone dimers connected by …

An elegant and efficient synthesis of heterocycles integrated with bisN‐acyl pyrazoline and bis‐1, 2, 3‐triazole via a green synthetic methodology

A Vellingiri, D Murugan, G Gnana Kumar… - Journal of …, 2021 - Wiley Online Library
Highly efficient and sustainable one‐pot multicomponent synthetic protocol has been
accomplished for the synthesis of novel bis‐N‐substituted pyrazolinyl‐1, 2, 3‐triazole …

Structural correlation and computational quantum chemical explorations of two 1, 2, 3-triazolyl-methoxypyridine derivatives as CYP51 antifungal inhibitors

C Ravikumar, S Murugavel - Structural Chemistry, 2019 - Springer
Structural correlation and computational quantum chemical optimization of two 1, 2, 3-
triazolyl-methoxypyridine derivatives fused with a five-membered heterocyclic moiety, furan …