Standardised practices in the networked management of congenital hyperinsulinism: a UK national collaborative consensus

MG Shaikh, AK Lucas-Herald, A Dastamani… - Frontiers in …, 2023 - frontiersin.org
Congenital hyperinsulinism (CHI) is a condition characterised by severe and recurrent
hypoglycaemia in infants and young children caused by inappropriate insulin over …

Diazoxide for neonatal hyperinsulinemic hypoglycemia and pulmonary hypertension

S Newman-Lindsay, S Lakshminrusimha, D Sankaran - Children, 2022 - mdpi.com
Hypoglycemia in neonates is associated with long-term neurodevelopmental effects.
Hyperinsulinemic hypoglycemia (HH) is the most common cause of persistent hypoglycemia …

Safety and efficacy of low-dose diazoxide in small-for-gestational-age infants with hyperinsulinaemic hypoglycaemia

S Chandran, RR Pravin, CM Chien, SE Saffari… - Archives of Disease in …, 2022 - fn.bmj.com
Objectives Diazoxide (DZX) is the drug of choice for treating hyperinsulinaemic
hypoglycaemia (HH), and it has potentially serious adverse effects. We studied the safety …

Low‐dose diazoxide is safe and effective in infants with transient hyperinsulinism

N Malhotra, D Yau, A Cunjamalay… - Clinical …, 2024 - Wiley Online Library
Objective Transient hyperinsulinism (THI) is the most common form of recurrent
hypoglycaemia in neonates beyond the first week of life. Although self‐resolving, treatment …

Oral diazoxide versus placebo for severe or recurrent neonatal hypoglycaemia: Neonatal Glucose Care Optimisation (NeoGluCO) study–a randomised controlled trial

D Laing, E Walsh, JM Alsweiler, SM Hanning… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Infants with severe or recurrent transitional hypoglycaemia continue to have
high rates of adverse neurological outcomes and new treatment approaches are needed …

Does the use of diazoxide for hyperinsulinaemic hypoglycaemia increase the risk of necrotising enterocolitis in neonates?

G Solís-García, T Yeung, B Jasani - Archives of Disease in Childhood, 2023 - adc.bmj.com
A 334/7 weeks' gestation male neonate, small for gestational age secondary to placental
insufficiency (birth weight 1309 g, second centile) is admitted to the neonatal intensive care …

Case 30-2022: A Newborn Girl with Hypoglycemia

S Sen, SJ Westra, JD Matute… - … England Journal of …, 2022 - Mass Medical Soc
Case 30-2022: A Newborn Girl with Hypoglycemia | New England Journal of Medicine Skip to
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Variability in Diagnosis and Management of Hypoglycemia in Neonatal Intensive Care Unit

D Dinu, JL Hagan, PJ Rozance - American Journal of …, 2024 - thieme-connect.com
Objective Hypoglycemia, the most common metabolic derangement in the newborn period
remains a contentious issue, not only due to various numerical definitions, but also due to …

Asymptomatic Hyperinsulinemic Hypoglycemia and Grade 4 Intraventricular Hemorrhage in a Late Preterm Infant

JL Banas, B Viswalingam… - … High Impact Case …, 2021 - journals.sagepub.com
Hyperinsulinemic hypoglycemia (HH) has the potential to cause acute neurologic
dysfunction and neurodevelopmental impairment. Parieto-occipital neuronal injuries have …

Neonatal hyperinsulinism: a retrospective study of presentation and management in a tertiary neonatal intensive care unit in the UK

MS Kalogeropoulou, H Couch, A Thankamony… - Archives of Disease in …, 2024 - fn.bmj.com
Objective Reports of hyperinsulinism typically focus on infants managed by highly
specialised services. However, neonates with hyperinsulinism are initially managed by …